Cargando…
Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities
Fibrous materials composed of core–sheath fibers from poly(ethylene oxide) (PEO), beeswax (BW) and 5-nitro-8-hydroxyquinoline (NQ) were prepared via the self-organization of PEO and BW during the single-spinneret electrospinning of a homogeneous blend solution of the partners. Additionally, the appl...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343633/ https://www.ncbi.nlm.nih.gov/pubmed/37445197 http://dx.doi.org/10.3390/ma16134882 |
_version_ | 1785072783413215232 |
---|---|
author | Kyuchyuk, Selin Paneva, Dilyana Manolova, Nevena Rashkov, Iliya Karashanova, Daniela Naydenov, Mladen Markova, Nadya |
author_facet | Kyuchyuk, Selin Paneva, Dilyana Manolova, Nevena Rashkov, Iliya Karashanova, Daniela Naydenov, Mladen Markova, Nadya |
author_sort | Kyuchyuk, Selin |
collection | PubMed |
description | Fibrous materials composed of core–sheath fibers from poly(ethylene oxide) (PEO), beeswax (BW) and 5-nitro-8-hydroxyquinoline (NQ) were prepared via the self-organization of PEO and BW during the single-spinneret electrospinning of a homogeneous blend solution of the partners. Additionally, the application of the same approach enabled the preparation of fibrous materials composed of core–double sheath fibers from PEO, poly(L-lactide) (PLA) and NQ or 5-chloro-7-iodo-8-hydroxyquinoline (CQ), as well as from PEO, poly(ε-caprolactone) (PCL) and NQ. The consecutive selective extraction of BW and of the polyester with hexane and tetrahydrofuran, respectively, evidenced that core–double sheath fibers from PEO/polyester/BW/drug consisted of a PEO core, a polyester inner sheath and a BW outer sheath. In order to evaluate the possibility of the application of fibrous materials from PEO/BW/NQ, PEO/PLA/BW/NQ, PEO/PCL/BW/NQ and PEO/PLA/BW/CQ for plant protection, microbiological studies were performed using both phytopathogenic microorganisms (Pseudomonas corrugata, Fusarium graminearum and Fusarium avenaceum) and beneficial microorganisms (Pseudomonas chlororaphis, Bacillus amyloliquefaciens and Trichoderma asperellum). It was found that the fibrous materials had anti-bacterial and anti-fungal activity against both phytopathogenic and beneficial microorganisms. This is the first report on the activity of fibrous materials loaded with 8-hydroxyquinoline derivatives not only against phytopathogenic but also against beneficial microorganisms that are of importance in agriculture. |
format | Online Article Text |
id | pubmed-10343633 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103436332023-07-14 Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities Kyuchyuk, Selin Paneva, Dilyana Manolova, Nevena Rashkov, Iliya Karashanova, Daniela Naydenov, Mladen Markova, Nadya Materials (Basel) Article Fibrous materials composed of core–sheath fibers from poly(ethylene oxide) (PEO), beeswax (BW) and 5-nitro-8-hydroxyquinoline (NQ) were prepared via the self-organization of PEO and BW during the single-spinneret electrospinning of a homogeneous blend solution of the partners. Additionally, the application of the same approach enabled the preparation of fibrous materials composed of core–double sheath fibers from PEO, poly(L-lactide) (PLA) and NQ or 5-chloro-7-iodo-8-hydroxyquinoline (CQ), as well as from PEO, poly(ε-caprolactone) (PCL) and NQ. The consecutive selective extraction of BW and of the polyester with hexane and tetrahydrofuran, respectively, evidenced that core–double sheath fibers from PEO/polyester/BW/drug consisted of a PEO core, a polyester inner sheath and a BW outer sheath. In order to evaluate the possibility of the application of fibrous materials from PEO/BW/NQ, PEO/PLA/BW/NQ, PEO/PCL/BW/NQ and PEO/PLA/BW/CQ for plant protection, microbiological studies were performed using both phytopathogenic microorganisms (Pseudomonas corrugata, Fusarium graminearum and Fusarium avenaceum) and beneficial microorganisms (Pseudomonas chlororaphis, Bacillus amyloliquefaciens and Trichoderma asperellum). It was found that the fibrous materials had anti-bacterial and anti-fungal activity against both phytopathogenic and beneficial microorganisms. This is the first report on the activity of fibrous materials loaded with 8-hydroxyquinoline derivatives not only against phytopathogenic but also against beneficial microorganisms that are of importance in agriculture. MDPI 2023-07-07 /pmc/articles/PMC10343633/ /pubmed/37445197 http://dx.doi.org/10.3390/ma16134882 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kyuchyuk, Selin Paneva, Dilyana Manolova, Nevena Rashkov, Iliya Karashanova, Daniela Naydenov, Mladen Markova, Nadya Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities |
title | Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities |
title_full | Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities |
title_fullStr | Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities |
title_full_unstemmed | Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities |
title_short | Electrospun Fibers of Biocompatible and Biodegradable Polyesters, Poly(Ethylene Oxide) and Beeswax with Anti-Bacterial and Anti-Fungal Activities |
title_sort | electrospun fibers of biocompatible and biodegradable polyesters, poly(ethylene oxide) and beeswax with anti-bacterial and anti-fungal activities |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343633/ https://www.ncbi.nlm.nih.gov/pubmed/37445197 http://dx.doi.org/10.3390/ma16134882 |
work_keys_str_mv | AT kyuchyukselin electrospunfibersofbiocompatibleandbiodegradablepolyesterspolyethyleneoxideandbeeswaxwithantibacterialandantifungalactivities AT panevadilyana electrospunfibersofbiocompatibleandbiodegradablepolyesterspolyethyleneoxideandbeeswaxwithantibacterialandantifungalactivities AT manolovanevena electrospunfibersofbiocompatibleandbiodegradablepolyesterspolyethyleneoxideandbeeswaxwithantibacterialandantifungalactivities AT rashkoviliya electrospunfibersofbiocompatibleandbiodegradablepolyesterspolyethyleneoxideandbeeswaxwithantibacterialandantifungalactivities AT karashanovadaniela electrospunfibersofbiocompatibleandbiodegradablepolyesterspolyethyleneoxideandbeeswaxwithantibacterialandantifungalactivities AT naydenovmladen electrospunfibersofbiocompatibleandbiodegradablepolyesterspolyethyleneoxideandbeeswaxwithantibacterialandantifungalactivities AT markovanadya electrospunfibersofbiocompatibleandbiodegradablepolyesterspolyethyleneoxideandbeeswaxwithantibacterialandantifungalactivities |