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Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric
An increase in textile resistance to antimicrobial agents has posed a pressing need for the development of new antimicrobials. Therefore, the antimicrobial characteristics of thiophene and pyridine acetohydrazide derivatives have been developed as novel textile-modified complexes exhibiting antibact...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343757/ https://www.ncbi.nlm.nih.gov/pubmed/37445199 http://dx.doi.org/10.3390/ma16134885 |
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author | Saeed, Saeed El-Sayed Aldubayyan, Meaad Al-Hakimi, Ahmed N. El-Hady, Marwa M. Abd |
author_facet | Saeed, Saeed El-Sayed Aldubayyan, Meaad Al-Hakimi, Ahmed N. El-Hady, Marwa M. Abd |
author_sort | Saeed, Saeed El-Sayed |
collection | PubMed |
description | An increase in textile resistance to antimicrobial agents has posed a pressing need for the development of new antimicrobials. Therefore, the antimicrobial characteristics of thiophene and pyridine acetohydrazide derivatives have been developed as novel textile-modified complexes exhibiting antibacterial agents. Synthesis and characterization of pyridyl-thienyl acetohydrazide derivative (AHZ) using NMR ((13)C and (1)H) and FTIR. Modification of cotton fabric (CF) with acetohydrazide (AHZ) and metal chlorides of divalent Cr, Mn, Co, Ni, Cu, and Zn and trivalent Fe, and Cr. SEM-EDX and Fourier-transform infrared were utilized to characterize cellulose-based cotton fabric (CF) attached to AHZ and their metal (M) complexes. Antimicrobial activity was examined against two types of bacteria, namely S. aureus and E. coli, and two types of fungi, namely C. albicans and A. flavus. All modified samples exhibited higher efficiency towards bacterial strains than fungal strains. In addition, cellulose modified with Ni (II) confers the most antibacterial protection efficiency. |
format | Online Article Text |
id | pubmed-10343757 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103437572023-07-14 Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric Saeed, Saeed El-Sayed Aldubayyan, Meaad Al-Hakimi, Ahmed N. El-Hady, Marwa M. Abd Materials (Basel) Article An increase in textile resistance to antimicrobial agents has posed a pressing need for the development of new antimicrobials. Therefore, the antimicrobial characteristics of thiophene and pyridine acetohydrazide derivatives have been developed as novel textile-modified complexes exhibiting antibacterial agents. Synthesis and characterization of pyridyl-thienyl acetohydrazide derivative (AHZ) using NMR ((13)C and (1)H) and FTIR. Modification of cotton fabric (CF) with acetohydrazide (AHZ) and metal chlorides of divalent Cr, Mn, Co, Ni, Cu, and Zn and trivalent Fe, and Cr. SEM-EDX and Fourier-transform infrared were utilized to characterize cellulose-based cotton fabric (CF) attached to AHZ and their metal (M) complexes. Antimicrobial activity was examined against two types of bacteria, namely S. aureus and E. coli, and two types of fungi, namely C. albicans and A. flavus. All modified samples exhibited higher efficiency towards bacterial strains than fungal strains. In addition, cellulose modified with Ni (II) confers the most antibacterial protection efficiency. MDPI 2023-07-07 /pmc/articles/PMC10343757/ /pubmed/37445199 http://dx.doi.org/10.3390/ma16134885 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Saeed, Saeed El-Sayed Aldubayyan, Meaad Al-Hakimi, Ahmed N. El-Hady, Marwa M. Abd Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric |
title | Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric |
title_full | Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric |
title_fullStr | Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric |
title_full_unstemmed | Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric |
title_short | Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric |
title_sort | synthesis and characterization of pyridine acetohydrazide derivative for antimicrobial cotton fabric |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343757/ https://www.ncbi.nlm.nih.gov/pubmed/37445199 http://dx.doi.org/10.3390/ma16134885 |
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