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Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric

An increase in textile resistance to antimicrobial agents has posed a pressing need for the development of new antimicrobials. Therefore, the antimicrobial characteristics of thiophene and pyridine acetohydrazide derivatives have been developed as novel textile-modified complexes exhibiting antibact...

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Autores principales: Saeed, Saeed El-Sayed, Aldubayyan, Meaad, Al-Hakimi, Ahmed N., El-Hady, Marwa M. Abd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343757/
https://www.ncbi.nlm.nih.gov/pubmed/37445199
http://dx.doi.org/10.3390/ma16134885
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author Saeed, Saeed El-Sayed
Aldubayyan, Meaad
Al-Hakimi, Ahmed N.
El-Hady, Marwa M. Abd
author_facet Saeed, Saeed El-Sayed
Aldubayyan, Meaad
Al-Hakimi, Ahmed N.
El-Hady, Marwa M. Abd
author_sort Saeed, Saeed El-Sayed
collection PubMed
description An increase in textile resistance to antimicrobial agents has posed a pressing need for the development of new antimicrobials. Therefore, the antimicrobial characteristics of thiophene and pyridine acetohydrazide derivatives have been developed as novel textile-modified complexes exhibiting antibacterial agents. Synthesis and characterization of pyridyl-thienyl acetohydrazide derivative (AHZ) using NMR ((13)C and (1)H) and FTIR. Modification of cotton fabric (CF) with acetohydrazide (AHZ) and metal chlorides of divalent Cr, Mn, Co, Ni, Cu, and Zn and trivalent Fe, and Cr. SEM-EDX and Fourier-transform infrared were utilized to characterize cellulose-based cotton fabric (CF) attached to AHZ and their metal (M) complexes. Antimicrobial activity was examined against two types of bacteria, namely S. aureus and E. coli, and two types of fungi, namely C. albicans and A. flavus. All modified samples exhibited higher efficiency towards bacterial strains than fungal strains. In addition, cellulose modified with Ni (II) confers the most antibacterial protection efficiency.
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spelling pubmed-103437572023-07-14 Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric Saeed, Saeed El-Sayed Aldubayyan, Meaad Al-Hakimi, Ahmed N. El-Hady, Marwa M. Abd Materials (Basel) Article An increase in textile resistance to antimicrobial agents has posed a pressing need for the development of new antimicrobials. Therefore, the antimicrobial characteristics of thiophene and pyridine acetohydrazide derivatives have been developed as novel textile-modified complexes exhibiting antibacterial agents. Synthesis and characterization of pyridyl-thienyl acetohydrazide derivative (AHZ) using NMR ((13)C and (1)H) and FTIR. Modification of cotton fabric (CF) with acetohydrazide (AHZ) and metal chlorides of divalent Cr, Mn, Co, Ni, Cu, and Zn and trivalent Fe, and Cr. SEM-EDX and Fourier-transform infrared were utilized to characterize cellulose-based cotton fabric (CF) attached to AHZ and their metal (M) complexes. Antimicrobial activity was examined against two types of bacteria, namely S. aureus and E. coli, and two types of fungi, namely C. albicans and A. flavus. All modified samples exhibited higher efficiency towards bacterial strains than fungal strains. In addition, cellulose modified with Ni (II) confers the most antibacterial protection efficiency. MDPI 2023-07-07 /pmc/articles/PMC10343757/ /pubmed/37445199 http://dx.doi.org/10.3390/ma16134885 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Saeed, Saeed El-Sayed
Aldubayyan, Meaad
Al-Hakimi, Ahmed N.
El-Hady, Marwa M. Abd
Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric
title Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric
title_full Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric
title_fullStr Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric
title_full_unstemmed Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric
title_short Synthesis and Characterization of Pyridine Acetohydrazide Derivative for Antimicrobial Cotton Fabric
title_sort synthesis and characterization of pyridine acetohydrazide derivative for antimicrobial cotton fabric
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343757/
https://www.ncbi.nlm.nih.gov/pubmed/37445199
http://dx.doi.org/10.3390/ma16134885
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