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Chemical Synthesis, Safety and Efficacy of Antihypertensive Candidate Drug 221s (2,9)
Hypertension is the main risk factor of cardiovascular and cerebrovascular diseases. In this paper, a novel compound known as 221s (2,9), which includes tanshinol, borneol and a mother nucleus of ACEI, was synthesized by condensation esterification, deprotection, amidation, deprotection, and amidati...
Autores principales: | Qin, Bei, Yu, Lili, Wang, Rong, Tang, Yimei, Chen, Yunmei, Wang, Nana, Zhang, Yixin, Tan, Xiong, Yang, Kuan, Zhang, Bo, He, Maofang, Zhang, Yuzhen, Hu, Yaqi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343876/ https://www.ncbi.nlm.nih.gov/pubmed/37446639 http://dx.doi.org/10.3390/molecules28134975 |
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