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Development of a native-locus dual reporter system for the efficient screening of the hyper-production of natural products in Streptomyces
Streptomyces is renowned for its abundant production of bioactive secondary metabolites, but most of these natural products are produced in low yields. Traditional rational network refactoring is highly dependent on the comprehensive understanding of regulatory mechanisms and multiple manipulations...
Autores principales: | Zhou, Jing-Yi, Ma, Bin-Bin, Zhao, Qing-Wei, Mao, Xu-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10343952/ https://www.ncbi.nlm.nih.gov/pubmed/37456716 http://dx.doi.org/10.3389/fbioe.2023.1225849 |
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