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Lipin knockdown in pan-neuron of Drosophila induces reduction of lifespan, deficient locomotive behavior, and abnormal morphology of motor neuron

The Lipin family is evolutionarily conserved among insects and mammals, and its crucial roles in lipid synthesis and homeostatic control of energy balance have been well documented. This study investigated the function of Lipin in neuronal function and neurodegeneration. The GAL4/UAS system was used...

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Detalles Bibliográficos
Autores principales: Nguyen, Yen D. H., Yoshida, Hideki, Tran, Thanh Men, Kamei, Kaeko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344432/
https://www.ncbi.nlm.nih.gov/pubmed/37470742
http://dx.doi.org/10.1097/WNR.0000000000001936