The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression

The NADPH oxidase NOX4 plays a tumor‐suppressor function in HCC. Silencing NOX4 confers higher proliferative and migratory capacity to HCC cells and increases their in vivo tumorigenic potential in xenografts in mice. NOX4 gene deletions are frequent in HCC, correlating with higher tumor grade and w...

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Detalles Bibliográficos
Autores principales: Peñuelas‐Haro, Irene, Espinosa‐Sotelo, Rut, Crosas‐Molist, Eva, Herranz‐Itúrbide, Macarena, Caballero‐Díaz, Daniel, Alay, Ania, Solé, Xavier, Ramos, Emilio, Serrano, Teresa, Martínez‐Chantar, María L., Knaus, Ulla G., Cuezva, José M., Zorzano, Antonio, Bertran, Esther, Fabregat, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Original Articles: Liver Cancer
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344438/
https://www.ncbi.nlm.nih.gov/pubmed/35920301
http://dx.doi.org/10.1002/hep.32702

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344438/
https://www.ncbi.nlm.nih.gov/pubmed/35920301
http://dx.doi.org/10.1002/hep.32702

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