Cargando…

Construction and evaluation of the functional polygenic risk score for gastric cancer in a prospective cohort of the European population

BACKGROUND: A polygenic risk score (PRS) derived from 112 single-nucleotide polymorphisms (SNPs) for gastric cancer has been reported in Chinese populations (PRS-112). However, its performance in other populations is unknown. A functional PRS (fPRS) using functional SNPs (fSNPs) may improve the gene...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gu, Yuanliang, Yan, Caiwang, Wang, Tianpei, Hu, Beiping, Zhu, Meng, Jin, Guangfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344526/ https://www.ncbi.nlm.nih.gov/pubmed/37394533 http://dx.doi.org/10.1097/CM9.0000000000002716

Ejemplares similares

Healthy Diet, Polygenic Risk Score, and Upper Gastrointestinal Cancer Risk: A Prospective Study from UK Biobank
por: Liu, Wenmin, et al.
Publicado: (2023)

Genetic risk, metabolic syndrome, and gastrointestinal cancer risk: A prospective cohort study
por: Liu, Yaqian, et al.
Publicado: (2022)

Integration of GWAS and eQTL Analysis to Identify Risk Loci and Susceptibility Genes for Gastric Cancer
por: Ni, Jing, et al.
Publicado: (2020)

Functional polymorphisms in NR3C1 are associated with gastric cancer risk in Chinese population
por: Gu, Yayun, et al.
Publicado: (2017)

Polygenic Risk Score, Lifestyles, and Type 2 Diabetes Risk: A Prospective Chinese Cohort Study
por: Liu, Jia, et al.
Publicado: (2023)

Polygenic score: An anchor holding the whole life course
por: Jin, Guangfu, et al.
Publicado: (2023)

The construction of cross-population polygenic risk scores using transfer learning
por: Zhao, Zhangchen, et al.
Publicado: (2022)

Evaluating Approaches for Constructing Polygenic Risk Scores for Prostate Cancer in Men of African and European Ancestry
por: Darst, Burcu F., et al.
Publicado: (2023)

Genetic variants in PPP2CA are associated with gastric cancer risk in a Chinese population
por: Huang, Tongtong, et al.
Publicado: (2017)

Construction and Application of Polygenic Risk Scores in Autoimmune Diseases
por: Khunsriraksakul, Chachrit, et al.
Publicado: (2022)

Evaluation of polygenic risk score for risk prediction of gastric cancer
por: Wang, Xiao-Yu, et al.
Publicado: (2023)

Polygenic Scores for Height in Admixed Populations
por: Bitarello, Bárbara D., et al.
Publicado: (2020)

Prospects for using risk scores in polygenic medicine
por: Lewis, Cathryn M., et al.
Publicado: (2017)

Independent evaluation of melanoma polygenic risk scores in UK and Australian prospective cohorts
por: Steinberg, Julia, et al.
Publicado: (2022)

Polygenic risk scores for the prediction of common cancers in East Asians: A population-based prospective cohort study
por: Ho, Peh Joo, et al.
Publicado: (2023)

A Principal Component Informed Approach to Address Polygenic Risk Score Transferability Across European Cohorts
por: Pärna, Katri, et al.
Publicado: (2022)

Role of Polygenic Risk Score in Cancer Precision Medicine of Non-European Populations: A Systematic Review
por: Junior, Howard Lopes Ribeiro, et al.
Publicado: (2022)

Prediction of gastric cancer risk by a polygenic risk score of Helicobacter pylori
por: Wang, Xiao-Yu, et al.
Publicado: (2022)

A nomogram for prediction of stage III/IV gastric cancer outcome after surgery: A multicenter population‐based study
por: Gao, Zhiying, et al.
Publicado: (2020)

Headaches and polygenic scores
por: Vilhjálmsson, Bjarni J., et al.
Publicado: (2019)

Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study
por: Yang, Xin, et al.
Publicado: (2018)

Polygenic Risk Score in African populations: progress and challenges
por: Adam, Yagoub, et al.
Publicado: (2023)

Development, validation, and evaluation of a risk assessment tool for personalized screening of gastric cancer in Chinese populations
por: Zhu, Xia, et al.
Publicado: (2023)

Risk assessment for colorectal cancer via polygenic risk score and lifestyle exposure: a large-scale association study of East Asian and European populations
por: Xin, Junyi, et al.
Publicado: (2023)

Genetic Variation in the 3'-Untranslated Region of NBN Gene Is Associated with Gastric Cancer Risk in a Chinese Population
por: Sun, Ping, et al.
Publicado: (2015)

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores
por: Albiñana, Clara, et al.
Publicado: (2023)

Interpreting polygenic scores, polygenic adaptation, and human phenotypic differences
por: Rosenberg, Noah A, et al.
Publicado: (2018)

Constructing a polygenic risk score for childhood obesity using functional data analysis
por: Craig, Sarah J.C., et al.
Publicado: (2023)

Polygenic Score for Body Mass Index Is Associated with Disordered Eating in a General Population Cohort
por: Abdulkadir, Mohamed, et al.
Publicado: (2020)

Population differentiation of polygenic score predictions under stabilizing selection
por: Yair, Sivan, et al.
Publicado: (2022)

Genotype imputation and polygenic score estimation in northwestern Russian population
por: Kolosov, Nikita, et al.
Publicado: (2022)

Understanding polygenic models, their development and the potential application of polygenic scores in healthcare
por: Babb de Villiers, Chantal, et al.
Publicado: (2020)

Multivariate extension of penalized regression on summary statistics to construct polygenic risk scores for correlated traits
por: Bahda, Meriem, et al.
Publicado: (2023)

Neurogenetic mechanisms of risk for ADHD: Examining associations of polygenic scores and brain volumes in a population cohort
por: He, Quanfa, et al.
Publicado: (2023)

European polygenic risk score for prediction of breast cancer shows similar performance in Asian women
por: Ho, Weang-Kee, et al.
Publicado: (2020)

Generalizability of Polygenic Risk Scores for Breast Cancer Among Women With European, African, and Latinx Ancestry
por: Liu, Cong, et al.
Publicado: (2021)

Polygenic risk score for hypercholesterolemia in a Brazilian familial hypercholesterolemia cohort
por: Lima, Isabella Ramos, et al.
Publicado: (2022)

Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries
por: Liang, Yanyu, et al.
Publicado: (2022)

Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
por: Huynh-Le, Minh-Phuong, et al.
Publicado: (2021)

Prospective Evaluation of the Addition of Polygenic Risk Scores to Breast Cancer Risk Models
por: Li, Sherly X, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ghueuo5s5v7g8t49vhbgm0t23q