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Construction and evaluation of the functional polygenic risk score for gastric cancer in a prospective cohort of the European population

BACKGROUND: A polygenic risk score (PRS) derived from 112 single-nucleotide polymorphisms (SNPs) for gastric cancer has been reported in Chinese populations (PRS-112). However, its performance in other populations is unknown. A functional PRS (fPRS) using functional SNPs (fSNPs) may improve the gene...

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Detalles Bibliográficos
Autores principales:	Gu, Yuanliang, Yan, Caiwang, Wang, Tianpei, Hu, Beiping, Zhu, Meng, Jin, Guangfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344526/ https://www.ncbi.nlm.nih.gov/pubmed/37394533 http://dx.doi.org/10.1097/CM9.0000000000002716

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