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Prediction of response to sofosbuvir-based therapy using serum interleukin-12 and single nucleotide polymorphism of the interleukin 28B gene as predictive factors in HCV positive genotype-4 patients

Some hepatitis-C virus patients have resistance to direct-acting-antivirals (DAAs). Genetic polymorphisms have been associated with drug resistance. This study aimed to evaluate the role of interleukin (IL)-28B gene polymorphism and IL-12 levels as predictors for a response to sofosbuvir/ribavirin (...

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Detalles Bibliográficos
Autores principales: Mohamed Abdelnajid, Doaa, Elmowafy, Ahmed Y., Rostaing, Lionel, Elrakaiby, Marwa T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344568/
https://www.ncbi.nlm.nih.gov/pubmed/37443472
http://dx.doi.org/10.1097/MD.0000000000034125

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