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Prediction of response to sofosbuvir-based therapy using serum interleukin-12 and single nucleotide polymorphism of the interleukin 28B gene as predictive factors in HCV positive genotype-4 patients
Some hepatitis-C virus patients have resistance to direct-acting-antivirals (DAAs). Genetic polymorphisms have been associated with drug resistance. This study aimed to evaluate the role of interleukin (IL)-28B gene polymorphism and IL-12 levels as predictors for a response to sofosbuvir/ribavirin (...
Autores principales: | Mohamed Abdelnajid, Doaa, Elmowafy, Ahmed Y., Rostaing, Lionel, Elrakaiby, Marwa T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott Williams & Wilkins
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344568/ https://www.ncbi.nlm.nih.gov/pubmed/37443472 http://dx.doi.org/10.1097/MD.0000000000034125 |
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