Cargando…
A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Occurred in Postchemotherapy of Breast Cancer
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy that arises from plasmacytoid dendritic cells. BPDCN typically presents with skin lesions and may involve peripheral blood, bone marrow, lymph nodes, or extranodal sites. It usually arises de...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344635/ https://www.ncbi.nlm.nih.gov/pubmed/37457315 http://dx.doi.org/10.1155/2023/7573037 |
_version_ | 1785072902412959744 |
---|---|
author | Tong, Jiankun Aksenov, Sergei Siegel, Beth M. Wei, Lihong Rodgers, William H. |
author_facet | Tong, Jiankun Aksenov, Sergei Siegel, Beth M. Wei, Lihong Rodgers, William H. |
author_sort | Tong, Jiankun |
collection | PubMed |
description | Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy that arises from plasmacytoid dendritic cells. BPDCN typically presents with skin lesions and may involve peripheral blood, bone marrow, lymph nodes, or extranodal sites. It usually arises de novo, and some BPDCN cases are associated with or develop into myeloid neoplasms. Here, we report a case of a 57-year-old female presenting with cervical lymphadenopathy and skin rashes during the COVID-19 pandemic in 2021 following multiple types of postmastectomy therapy for breast cancer. The patient was ultimately diagnosed with BPCDN by lymph node biopsy. To the best of our knowledge, this is the first case report of BPDCN occurring postchemotherapy of breast cancer. |
format | Online Article Text |
id | pubmed-10344635 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-103446352023-07-14 A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Occurred in Postchemotherapy of Breast Cancer Tong, Jiankun Aksenov, Sergei Siegel, Beth M. Wei, Lihong Rodgers, William H. Case Rep Hematol Case Report Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and highly aggressive hematologic malignancy that arises from plasmacytoid dendritic cells. BPDCN typically presents with skin lesions and may involve peripheral blood, bone marrow, lymph nodes, or extranodal sites. It usually arises de novo, and some BPDCN cases are associated with or develop into myeloid neoplasms. Here, we report a case of a 57-year-old female presenting with cervical lymphadenopathy and skin rashes during the COVID-19 pandemic in 2021 following multiple types of postmastectomy therapy for breast cancer. The patient was ultimately diagnosed with BPCDN by lymph node biopsy. To the best of our knowledge, this is the first case report of BPDCN occurring postchemotherapy of breast cancer. Hindawi 2023-07-06 /pmc/articles/PMC10344635/ /pubmed/37457315 http://dx.doi.org/10.1155/2023/7573037 Text en Copyright © 2023 Jiankun Tong et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Tong, Jiankun Aksenov, Sergei Siegel, Beth M. Wei, Lihong Rodgers, William H. A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Occurred in Postchemotherapy of Breast Cancer |
title | A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Occurred in Postchemotherapy of Breast Cancer |
title_full | A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Occurred in Postchemotherapy of Breast Cancer |
title_fullStr | A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Occurred in Postchemotherapy of Breast Cancer |
title_full_unstemmed | A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Occurred in Postchemotherapy of Breast Cancer |
title_short | A Rare Case of Blastic Plasmacytoid Dendritic Cell Neoplasm Occurred in Postchemotherapy of Breast Cancer |
title_sort | rare case of blastic plasmacytoid dendritic cell neoplasm occurred in postchemotherapy of breast cancer |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344635/ https://www.ncbi.nlm.nih.gov/pubmed/37457315 http://dx.doi.org/10.1155/2023/7573037 |
work_keys_str_mv | AT tongjiankun ararecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer AT aksenovsergei ararecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer AT siegelbethm ararecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer AT weilihong ararecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer AT rodgerswilliamh ararecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer AT tongjiankun rarecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer AT aksenovsergei rarecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer AT siegelbethm rarecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer AT weilihong rarecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer AT rodgerswilliamh rarecaseofblasticplasmacytoiddendriticcellneoplasmoccurredinpostchemotherapyofbreastcancer |