Genomic Breakpoint Characterization and Transcriptome Analysis of Metastatic, Recurrent Desmoplastic Small Round Cell Tumor

Desmoplastic small round cell tumor (DSRCT) is a rare pediatric cancer caused by the EWSR1-WT1 fusion oncogene. Despite initial response to chemotherapy, DSRCT has a recurrence rate of over 80% leading to poor patient prognosis with a 5-year survival rate of only 15–25%. Owing to the rarity of DSRCT...

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Detalles Bibliográficos
Autores principales: Magrath, Justin W., Flinchum, Dane A., Hartono, Alifiani B., Goldberg, Ilon N., Espinosa-Cotton, Madelyn, Moroz, Krzysztof, Cheung, Nai-Kong V., Lee, Sean B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344636/
https://www.ncbi.nlm.nih.gov/pubmed/37457440
http://dx.doi.org/10.1155/2023/6686702

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