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A nonlinear relapse model with disaggregated contact rates: Analysis of a forward-backward bifurcation

Throughout the progress of epidemic scenarios, individuals in different health classes are expected to have different average daily contact behavior. This contact heterogeneity has been studied in recent adaptive models and allows us to capture the inherent differences across health statuses better....

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Detalles Bibliográficos
Autores principales: Calvo-Monge, Jimmy, Sanchez, Fabio, Calvo, Juan Gabriel, Mena, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344666/
https://www.ncbi.nlm.nih.gov/pubmed/37457645
http://dx.doi.org/10.1016/j.idm.2023.06.004
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author Calvo-Monge, Jimmy
Sanchez, Fabio
Calvo, Juan Gabriel
Mena, Dario
author_facet Calvo-Monge, Jimmy
Sanchez, Fabio
Calvo, Juan Gabriel
Mena, Dario
author_sort Calvo-Monge, Jimmy
collection PubMed
description Throughout the progress of epidemic scenarios, individuals in different health classes are expected to have different average daily contact behavior. This contact heterogeneity has been studied in recent adaptive models and allows us to capture the inherent differences across health statuses better. Diseases with reinfection bring out more complex scenarios and offer an important application to consider contact disaggregation. Therefore, we developed a nonlinear differential equation model to explore the dynamics of relapse phenomena and contact differences across health statuses. Our incidence rate function is formulated, taking inspiration from recent adaptive algorithms. It incorporates contact behavior for individuals in each health class. We use constant contact rates at each health status for our analytical results and prove conditions for different forward-backward bifurcation scenarios. The relationship between the different contact rates heavily influences these conditions. Numerical examples highlight the effect of temporarily recovered individuals and initial conditions on infected population persistence.
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spelling pubmed-103446662023-07-14 A nonlinear relapse model with disaggregated contact rates: Analysis of a forward-backward bifurcation Calvo-Monge, Jimmy Sanchez, Fabio Calvo, Juan Gabriel Mena, Dario Infect Dis Model Article Throughout the progress of epidemic scenarios, individuals in different health classes are expected to have different average daily contact behavior. This contact heterogeneity has been studied in recent adaptive models and allows us to capture the inherent differences across health statuses better. Diseases with reinfection bring out more complex scenarios and offer an important application to consider contact disaggregation. Therefore, we developed a nonlinear differential equation model to explore the dynamics of relapse phenomena and contact differences across health statuses. Our incidence rate function is formulated, taking inspiration from recent adaptive algorithms. It incorporates contact behavior for individuals in each health class. We use constant contact rates at each health status for our analytical results and prove conditions for different forward-backward bifurcation scenarios. The relationship between the different contact rates heavily influences these conditions. Numerical examples highlight the effect of temporarily recovered individuals and initial conditions on infected population persistence. KeAi Publishing 2023-06-30 /pmc/articles/PMC10344666/ /pubmed/37457645 http://dx.doi.org/10.1016/j.idm.2023.06.004 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Article
Calvo-Monge, Jimmy
Sanchez, Fabio
Calvo, Juan Gabriel
Mena, Dario
A nonlinear relapse model with disaggregated contact rates: Analysis of a forward-backward bifurcation
title A nonlinear relapse model with disaggregated contact rates: Analysis of a forward-backward bifurcation
title_full A nonlinear relapse model with disaggregated contact rates: Analysis of a forward-backward bifurcation
title_fullStr A nonlinear relapse model with disaggregated contact rates: Analysis of a forward-backward bifurcation
title_full_unstemmed A nonlinear relapse model with disaggregated contact rates: Analysis of a forward-backward bifurcation
title_short A nonlinear relapse model with disaggregated contact rates: Analysis of a forward-backward bifurcation
title_sort nonlinear relapse model with disaggregated contact rates: analysis of a forward-backward bifurcation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344666/
https://www.ncbi.nlm.nih.gov/pubmed/37457645
http://dx.doi.org/10.1016/j.idm.2023.06.004
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