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Tricarboxylic acid (TCA) cycle, sphingolipid, and phosphatidylcholine metabolism are dysregulated in T. gondii infection-induced cachexia
Cachexia is a life-threatening disease characterized by chronic, inflammatory muscle wasting and systemic metabolic impairment. Despite its high prevalence, there are no efficacious therapies for cachexia. Mice chronically infected with the protozoan parasite Toxoplasma gondii represent a novel anim...
Autores principales: | Feng, Tzu-Yu, Melchor, Stephanie J., Zhao, Xiao-Yu, Ghumman, Haider, Kester, Mark, Fox, Todd E., Ewald, Sarah E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344712/ https://www.ncbi.nlm.nih.gov/pubmed/37456044 http://dx.doi.org/10.1016/j.heliyon.2023.e17411 |
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