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Numerical computation of pulsatile hemodynamics and diagnostic concern of coronary bifurcated artery flow for Newtonian and non-Newtonian fluid
Atherosclerotic with the high occurrence of plaque formation due to stenosis has attracted wide attention among researchers. The left coronary artery has been studied in two-dimensional and in three-dimensional (3D) bifurcation as the models of blood flow through Newtonian and non-Newtonian fluids t...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344714/ https://www.ncbi.nlm.nih.gov/pubmed/37456052 http://dx.doi.org/10.1016/j.heliyon.2023.e17533 |
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author | Uddin, Md. Jashim Bangalee, M.Z.I. Ferdows, M. |
author_facet | Uddin, Md. Jashim Bangalee, M.Z.I. Ferdows, M. |
author_sort | Uddin, Md. Jashim |
collection | PubMed |
description | Atherosclerotic with the high occurrence of plaque formation due to stenosis has attracted wide attention among researchers. The left coronary artery has been studied in two-dimensional and in three-dimensional (3D) bifurcation as the models of blood flow through Newtonian and non-Newtonian fluids to better understand the physical mechanism. The computational Fluid Dynamics (CFD) technique is incorporated in COMSOL Multiphysics and then it is justified by satisfactory validation. It is found that the Newtonian model shows larger recirculation zones than non-Newtonian does. The present study also focuses on the evaluations of the lesion of diagnostic and the coefficient of pressure drop assessments on the basis of the diagnostic parameter’s critical values affected by the rheological model. Nevertheless, the leading concentration of the subsisting investigation works is confined to the change of importance factor [Formula: see text] affected by arterial blockage. But the IFc of non-Newtonian fluid for 3D left coronary artery bifurcation model decreases with increasing bifurcation angle and the time-averaged inlet pressure is the least for smaller bifurcation angles. The current research further concentrates that the flow separation length reduces with developing bifurcation angle in bifurcated geometry. It is significant to mention that non-Newtonian blood flow model incorporating hemodynamic and diagnostic parameters has great impacts on instantaneous flow systems. |
format | Online Article Text |
id | pubmed-10344714 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-103447142023-07-15 Numerical computation of pulsatile hemodynamics and diagnostic concern of coronary bifurcated artery flow for Newtonian and non-Newtonian fluid Uddin, Md. Jashim Bangalee, M.Z.I. Ferdows, M. Heliyon Research Article Atherosclerotic with the high occurrence of plaque formation due to stenosis has attracted wide attention among researchers. The left coronary artery has been studied in two-dimensional and in three-dimensional (3D) bifurcation as the models of blood flow through Newtonian and non-Newtonian fluids to better understand the physical mechanism. The computational Fluid Dynamics (CFD) technique is incorporated in COMSOL Multiphysics and then it is justified by satisfactory validation. It is found that the Newtonian model shows larger recirculation zones than non-Newtonian does. The present study also focuses on the evaluations of the lesion of diagnostic and the coefficient of pressure drop assessments on the basis of the diagnostic parameter’s critical values affected by the rheological model. Nevertheless, the leading concentration of the subsisting investigation works is confined to the change of importance factor [Formula: see text] affected by arterial blockage. But the IFc of non-Newtonian fluid for 3D left coronary artery bifurcation model decreases with increasing bifurcation angle and the time-averaged inlet pressure is the least for smaller bifurcation angles. The current research further concentrates that the flow separation length reduces with developing bifurcation angle in bifurcated geometry. It is significant to mention that non-Newtonian blood flow model incorporating hemodynamic and diagnostic parameters has great impacts on instantaneous flow systems. Elsevier 2023-07-03 /pmc/articles/PMC10344714/ /pubmed/37456052 http://dx.doi.org/10.1016/j.heliyon.2023.e17533 Text en © 2023 The Authors. Published by Elsevier Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Research Article Uddin, Md. Jashim Bangalee, M.Z.I. Ferdows, M. Numerical computation of pulsatile hemodynamics and diagnostic concern of coronary bifurcated artery flow for Newtonian and non-Newtonian fluid |
title | Numerical computation of pulsatile hemodynamics and diagnostic concern of coronary bifurcated artery flow for Newtonian and non-Newtonian fluid |
title_full | Numerical computation of pulsatile hemodynamics and diagnostic concern of coronary bifurcated artery flow for Newtonian and non-Newtonian fluid |
title_fullStr | Numerical computation of pulsatile hemodynamics and diagnostic concern of coronary bifurcated artery flow for Newtonian and non-Newtonian fluid |
title_full_unstemmed | Numerical computation of pulsatile hemodynamics and diagnostic concern of coronary bifurcated artery flow for Newtonian and non-Newtonian fluid |
title_short | Numerical computation of pulsatile hemodynamics and diagnostic concern of coronary bifurcated artery flow for Newtonian and non-Newtonian fluid |
title_sort | numerical computation of pulsatile hemodynamics and diagnostic concern of coronary bifurcated artery flow for newtonian and non-newtonian fluid |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344714/ https://www.ncbi.nlm.nih.gov/pubmed/37456052 http://dx.doi.org/10.1016/j.heliyon.2023.e17533 |
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