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Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem

We present a case of neonatal goiter caused by exposure to propylthiouracil (PTU) during pregnancy in this case report. The mother was treated with PTU while pregnant and had a history of Graves' illness. The baby had a neck tumor and was having breathing problems when they were first seen. A b...

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Autores principales: Saboo, Keyur, Gemnani, Rinkle R, Manuja, Nishtha, Kumar, Sunil, Acharya, Sourya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344733/
https://www.ncbi.nlm.nih.gov/pubmed/37456378
http://dx.doi.org/10.7759/cureus.40389
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author Saboo, Keyur
Gemnani, Rinkle R
Manuja, Nishtha
Kumar, Sunil
Acharya, Sourya
author_facet Saboo, Keyur
Gemnani, Rinkle R
Manuja, Nishtha
Kumar, Sunil
Acharya, Sourya
author_sort Saboo, Keyur
collection PubMed
description We present a case of neonatal goiter caused by exposure to propylthiouracil (PTU) during pregnancy in this case report. The mother was treated with PTU while pregnant and had a history of Graves' illness. The baby had a neck tumor and was having breathing problems when they were first seen. A big thyroid gland was detected by a neck CT scan. This instance serves as a reminder of the significance of managing maternal thyroid problems appropriately during pregnancy as well as the requirement for careful thyroid function monitoring in newborns exposed to PTU. Given the possible hazards to the growing baby, it also calls into question whether PTU is an effective first-line treatment for maternal Graves' illness during pregnancy. This case report highlights the importance of shared decision-making with patients (by discussing different treatment options and their side effects).
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spelling pubmed-103447332023-07-15 Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem Saboo, Keyur Gemnani, Rinkle R Manuja, Nishtha Kumar, Sunil Acharya, Sourya Cureus Internal Medicine We present a case of neonatal goiter caused by exposure to propylthiouracil (PTU) during pregnancy in this case report. The mother was treated with PTU while pregnant and had a history of Graves' illness. The baby had a neck tumor and was having breathing problems when they were first seen. A big thyroid gland was detected by a neck CT scan. This instance serves as a reminder of the significance of managing maternal thyroid problems appropriately during pregnancy as well as the requirement for careful thyroid function monitoring in newborns exposed to PTU. Given the possible hazards to the growing baby, it also calls into question whether PTU is an effective first-line treatment for maternal Graves' illness during pregnancy. This case report highlights the importance of shared decision-making with patients (by discussing different treatment options and their side effects). Cureus 2023-06-13 /pmc/articles/PMC10344733/ /pubmed/37456378 http://dx.doi.org/10.7759/cureus.40389 Text en Copyright © 2023, Saboo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Saboo, Keyur
Gemnani, Rinkle R
Manuja, Nishtha
Kumar, Sunil
Acharya, Sourya
Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem
title Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem
title_full Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem
title_fullStr Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem
title_full_unstemmed Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem
title_short Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem
title_sort propylthiouracil-induced neonatal goiter: an avoidable problem
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344733/
https://www.ncbi.nlm.nih.gov/pubmed/37456378
http://dx.doi.org/10.7759/cureus.40389
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