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Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem
We present a case of neonatal goiter caused by exposure to propylthiouracil (PTU) during pregnancy in this case report. The mother was treated with PTU while pregnant and had a history of Graves' illness. The baby had a neck tumor and was having breathing problems when they were first seen. A b...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344733/ https://www.ncbi.nlm.nih.gov/pubmed/37456378 http://dx.doi.org/10.7759/cureus.40389 |
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author | Saboo, Keyur Gemnani, Rinkle R Manuja, Nishtha Kumar, Sunil Acharya, Sourya |
author_facet | Saboo, Keyur Gemnani, Rinkle R Manuja, Nishtha Kumar, Sunil Acharya, Sourya |
author_sort | Saboo, Keyur |
collection | PubMed |
description | We present a case of neonatal goiter caused by exposure to propylthiouracil (PTU) during pregnancy in this case report. The mother was treated with PTU while pregnant and had a history of Graves' illness. The baby had a neck tumor and was having breathing problems when they were first seen. A big thyroid gland was detected by a neck CT scan. This instance serves as a reminder of the significance of managing maternal thyroid problems appropriately during pregnancy as well as the requirement for careful thyroid function monitoring in newborns exposed to PTU. Given the possible hazards to the growing baby, it also calls into question whether PTU is an effective first-line treatment for maternal Graves' illness during pregnancy. This case report highlights the importance of shared decision-making with patients (by discussing different treatment options and their side effects). |
format | Online Article Text |
id | pubmed-10344733 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-103447332023-07-15 Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem Saboo, Keyur Gemnani, Rinkle R Manuja, Nishtha Kumar, Sunil Acharya, Sourya Cureus Internal Medicine We present a case of neonatal goiter caused by exposure to propylthiouracil (PTU) during pregnancy in this case report. The mother was treated with PTU while pregnant and had a history of Graves' illness. The baby had a neck tumor and was having breathing problems when they were first seen. A big thyroid gland was detected by a neck CT scan. This instance serves as a reminder of the significance of managing maternal thyroid problems appropriately during pregnancy as well as the requirement for careful thyroid function monitoring in newborns exposed to PTU. Given the possible hazards to the growing baby, it also calls into question whether PTU is an effective first-line treatment for maternal Graves' illness during pregnancy. This case report highlights the importance of shared decision-making with patients (by discussing different treatment options and their side effects). Cureus 2023-06-13 /pmc/articles/PMC10344733/ /pubmed/37456378 http://dx.doi.org/10.7759/cureus.40389 Text en Copyright © 2023, Saboo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Saboo, Keyur Gemnani, Rinkle R Manuja, Nishtha Kumar, Sunil Acharya, Sourya Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem |
title | Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem |
title_full | Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem |
title_fullStr | Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem |
title_full_unstemmed | Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem |
title_short | Propylthiouracil-Induced Neonatal Goiter: An Avoidable Problem |
title_sort | propylthiouracil-induced neonatal goiter: an avoidable problem |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344733/ https://www.ncbi.nlm.nih.gov/pubmed/37456378 http://dx.doi.org/10.7759/cureus.40389 |
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