High density and proximity of CD8 (+) T cells to tumor cells are correlated with better response to nivolumab treatment in metastatic pleural mesothelioma

BACKGROUND: The efficacy of immune checkpoint inhibitors (ICIs) in pleural mesothelioma has recently been established. The response to ICIs can be predicted by quantitative analysis of cells and their spatial distribution in the tumor microenvironment (TME). However, the detailed composition of the...

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Detalles Bibliográficos
Autores principales: Yin, Yuting, Sakakibara, Rie, Honda, Takayuki, Kirimura, Susumu, Daroonpan, Pissacha, Kobayashi, Masashi, Ando, Kohei, Ujiie, Hideki, Kato, Tatsuya, Kaga, Kichizo, Mitsumura, Takahiro, Nakano, Ryoji, Sakashita, Hiroyuki, Matsuge, Shinichi, Ishibashi, Hironori, Akashi, Takumi, Hida, Yasuhiro, Morohoshi, Takao, Azuma, Miyuki, Okubo, Kenichi, Miyazaki, Yasunari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344741/
https://www.ncbi.nlm.nih.gov/pubmed/37253418
http://dx.doi.org/10.1111/1759-7714.14981

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