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Micheliolide attenuates neuroinflammation to improve cognitive impairment of Alzheimer's disease by inhibiting NF-κB and PI3K/Akt signaling pathways

Inflammatory reaction in the brain activates glial cells, and over-activated glial cells secrete inflammatory mediators, which aggravates the inflammatory response in the brain and accelerates the development of Alzheimer's disease (AD) in turn. Numerous natural compounds from herbs can allevia...

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Detalles Bibliográficos
Autores principales: Yang, Guizhen, Hu, You, Qin, Xiangyang, Sun, Jinxia, Miao, Zhulei, Wang, Lixin, Ke, Zunji, Zheng, Yuejuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344752/
https://www.ncbi.nlm.nih.gov/pubmed/37456020
http://dx.doi.org/10.1016/j.heliyon.2023.e17848