Cargando…

Micheliolide attenuates neuroinflammation to improve cognitive impairment of Alzheimer's disease by inhibiting NF-κB and PI3K/Akt signaling pathways

Inflammatory reaction in the brain activates glial cells, and over-activated glial cells secrete inflammatory mediators, which aggravates the inflammatory response in the brain and accelerates the development of Alzheimer's disease (AD) in turn. Numerous natural compounds from herbs can allevia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Guizhen, Hu, You, Qin, Xiangyang, Sun, Jinxia, Miao, Zhulei, Wang, Lixin, Ke, Zunji, Zheng, Yuejuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344752/ https://www.ncbi.nlm.nih.gov/pubmed/37456020 http://dx.doi.org/10.1016/j.heliyon.2023.e17848

Ejemplares similares

Astragaloside IV attenuates neuroinflammation and ameliorates cognitive impairment in Alzheimer’s disease via inhibiting NF-κB signaling pathway
por: He, Li, et al.
Publicado: (2023)

Micheliolide inhibits LPS-induced inflammatory response and protects mice from LPS challenge
por: Qin, Xiangyang, et al.
Publicado: (2016)

Quercitrin improved cognitive impairment through inhibiting inflammation induced by microglia in Alzheimer’s disease mice
por: Wang, Lixin, et al.
Publicado: (2022)

Micheliolide Attenuates Lipopolysaccharide-Induced Inflammation by Modulating the mROS/NF-κB/NLRP3 Axis in Renal Tubular Epithelial Cells
por: Lei, Xianghong, et al.
Publicado: (2020)

Micheliolide suppresses the viability, migration and invasion of U251MG cells via the NF-κB signaling pathway
por: Feng, Dingkun, et al.
Publicado: (2020)

Aggf1 attenuates neuroinflammation and BBB disruption via PI3K/Akt/NF-κB pathway after subarachnoid hemorrhage in rats
por: Zhu, Qiquan, et al.
Publicado: (2018)

Forsythoside B attenuates memory impairment and neuroinflammation via inhibition on NF-κB signaling in Alzheimer’s disease
por: Kong, Fan’ge, et al.
Publicado: (2020)

Micheliolide provides protection of mice against Staphylococcus aureus and MRSA infection by down-regulating inflammatory response
por: Jiang, Xinru, et al.
Publicado: (2017)

Micheliolide suppresses LPS-induced neuroinflammatory responses
por: Sun, Zhaomeng, et al.
Publicado: (2017)

MCL Plays an Anti-Inflammatory Role in Mycobacterium tuberculosis-Induced Immune Response by Inhibiting NF-κB and NLRP3 Inflammasome Activation
por: Zhang, Qingwen, et al.
Publicado: (2017)

(E)-13-(2-Bromophenyl)micheliolide
por: Penthala, Narsimha Reddy, et al.
Publicado: (2014)

Synthesis of Micheliolide Derivatives and Their Activities against AML Progenitor Cells
por: Ma, Wei-Wei, et al.
Publicado: (2013)

ACT001 attenuates microglia-mediated neuroinflammation after traumatic brain injury via inhibiting AKT/NFκB/NLRP3 pathway
por: Cai, Lin, et al.
Publicado: (2022)

Dihydroartemisinin attenuates autoimmune thyroiditis by inhibiting the CXCR3/PI3K/AKT/NF-κB signaling pathway
por: Liu, Huijuan, et al.
Publicado: (2017)

Dihydroartemisinin Attenuated Intervertebral Disc Degeneration via Inhibiting PI3K/AKT and NF-κB Signaling Pathways
por: Liao, Zhiheng, et al.
Publicado: (2022)

Micheliolide alleviates ankylosing spondylitis (AS) by suppressing the activation of the NLRP3 inflammasome and maintaining the balance of Th1/Th2 via regulating the NF-κB signaling pathway
por: Tian, Zhong-Gu, et al.
Publicado: (2020)

Oridonin Attenuates Aβ(1–42)-Induced Neuroinflammation and Inhibits NF-κB Pathway
por: Wang, Sulei, et al.
Publicado: (2014)

Micheliolide Derivative DMAMCL Inhibits Glioma Cell Growth In Vitro and In Vivo
por: An, Yinghong, et al.
Publicado: (2015)

Antineoplastic effects and mechanisms of micheliolide in acute myelogenous leukemia stem cells
por: Ji, Qing, et al.
Publicado: (2016)

Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway
por: Peng, Fenfen, et al.
Publicado: (2019)

Xuebijing Injection Alleviates Pam3CSK4-Induced Inflammatory Response and Protects Mice From Sepsis Caused by Methicillin-Resistant Staphylococcus aureus
por: Li, Tiantian, et al.
Publicado: (2020)

Tanshinone IIA attenuates neuroinflammation via inhibiting RAGE/NF-κB signaling pathway in vivo and in vitro
por: Ding, Bo, et al.
Publicado: (2020)

13-(N,N-Dimethylamino)micheliolide 0.08-hydrate
por: Bommagani, Shobanbabu, et al.
Publicado: (2013)

Correction: Micheliolide ameliorates renal fibrosis by suppressing the Mtdh/BMP/MAPK pathway
por: Peng, Fenfen, et al.
Publicado: (2019)

Critical roles of PI3K/Akt/NF-κB survival axis in angiotensin II-induced podocyte injury
por: Wang, Junjie, et al.
Publicado: (2019)

Activation of RARα Receptor Attenuates Neuroinflammation After SAH via Promoting M1-to-M2 Phenotypic Polarization of Microglia and Regulating Mafb/Msr1/PI3K-Akt/NF-κB Pathway
por: Tian, Yang, et al.
Publicado: (2022)

Luteolin Attenuates Hypertension via Inhibiting NF-κB-Mediated Inflammation and PI3K/Akt Signaling Pathway in the Hypothalamic Paraventricular Nucleus
por: Gao, Hong-Li, et al.
Publicado: (2023)

Carrageenophyte Kappaphycus malesianus Inhibits Microglia-Mediated Neuroinflammation via Suppression of AKT/NF-κB and ERK Signaling Pathways
por: Lai, Nicole Jean-Yean, et al.
Publicado: (2022)

Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway
por: Badshah, Haroon, et al.
Publicado: (2016)

Cytoglobin Attenuates Neuroinflammation in Lipopolysaccharide-Activated Primary Preoptic Area Cells via NF-κB Pathway Inhibition
por: Gomes, Bruna R. B., et al.
Publicado: (2019)

Hydroxychloroquine attenuates neuroinflammation following traumatic brain injury by regulating the TLR4/NF-κB signaling pathway
por: Hu, Jian, et al.
Publicado: (2022)

Chlorogenic Acid Attenuates Oxidative Stress-Induced Intestinal Epithelium Injury by Co-Regulating the PI3K/Akt and IκBα/NF-κB Signaling
por: Chen, Jiali, et al.
Publicado: (2021)

Targeting the PI3K/AKT/mTOR/NFκB Axis in Ovarian Cancer
por: Ghoneum, Alia, et al.
Publicado: (2020)

Dynamin-related protein 1 is involved in micheliolide-induced breast cancer cell death
por: Jia, Yongsheng, et al.
Publicado: (2015)

Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model
por: Stekic, Andjela, et al.
Publicado: (2022)

Neuron-derived FGF10 ameliorates cerebral ischemia injury via inhibiting NF-κB-dependent neuroinflammation and activating PI3K/Akt survival signaling pathway in mice
por: Li, Yong-Hua, et al.
Publicado: (2016)

4-(Hydroxymethyl)catechol Extracted From Fungi in Marine Sponges Attenuates Rheumatoid Arthritis by Inhibiting PI3K/Akt/NF-κB Signaling
por: Lee, Jong Y., et al.
Publicado: (2018)

Scutellaria baicalensis Attenuates Airway Remodeling via PI3K/Akt/NF-κB Pathway in Cigarette Smoke Mediated-COPD Rats Model
por: Xu, Fei, et al.
Publicado: (2018)

Ibrutinib attenuated DSS-induced ulcerative colitis, oxidative stress, and the inflammatory cascade by modulating the PI3K/Akt and JNK/NF-κB pathways
por: Hao, Liangliang, et al.
Publicado: (2022)

Inhibition of CCR2 attenuates neuroinflammation and neuronal apoptosis after subarachnoid hemorrhage through the PI3K/Akt pathway
por: Tian, Qi, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_d2gki850m9jubtb0pbltfq6nie