lncRNA XIST inhibition promotes M2 polarization of microglial and aggravates the spinal cord injury via regulating miR-124–3p / IRF1 axis

Spinal cord injury (SCI) has a high disability rate and mortality rate. Recently, LncRNA XIST has been found to be involved in the regulation of inflammatory responses. Therefore, we aimed to investigate the role of XIST in the occurrence and development of SCI and the specific regulation mechanism....

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Detalles Bibliográficos
Autores principales: Yang, Jin, Gong, Zhiqiang, Dong, Junjie, Bi, Hangchuan, Wang, Bing, Du, Kaili, Zhang, Chunqiang, Chen, Lingqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344764/
https://www.ncbi.nlm.nih.gov/pubmed/37455998
http://dx.doi.org/10.1016/j.heliyon.2023.e17852

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