Increased CaMKII activation and contrast changes of cardiac β1-and β3-Adrenergic signaling pathways in a humanized angiotensinogen model of hypertension

AIMS: Upregulation of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) contributes to the pathogenesis of cardiovascular disease, including hypertension. Transgenic rats expressing the human angiotensinogen gene [TGR (hAGT)L1623] are a new novel humanized model of hypertension that associates...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoqiang, Cao, Jing, Chen, Zhe, Liu, Yixi, VonCannon, Jessica L., Cheng, Heng Jie, Ferrario, Carlos M., Cheng, Che Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344767/
https://www.ncbi.nlm.nih.gov/pubmed/37456012
http://dx.doi.org/10.1016/j.heliyon.2023.e17851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344767/
https://www.ncbi.nlm.nih.gov/pubmed/37456012
http://dx.doi.org/10.1016/j.heliyon.2023.e17851

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