Dynamic de novo heterochromatin assembly and disassembly at replication forks ensures fork stability

Chromatin is dynamically reorganized when DNA replication forks are challenged. However, the process of epigenetic reorganization and its implication for fork stability is poorly understood. Here we discover a checkpoint-regulated cascade of chromatin signalling that activates the histone methyltran...

Descripción completa

Detalles Bibliográficos
Autores principales: Gaggioli, Vincent, Lo, Calvin S. Y., Reverón-Gómez, Nazaret, Jasencakova, Zuzana, Domenech, Heura, Nguyen, Hong, Sidoli, Simone, Tvardovskiy, Andrey, Uruci, Sidrit, Slotman, Johan A., Chai, Yi, Gonçalves, João G. S. C. Souto, Manolika, Eleni Maria, Jensen, Ole N., Wheeler, David, Sridharan, Sriram, Chakrabarty, Sanjiban, Demmers, Jeroen, Kanaar, Roland, Groth, Anja, Taneja, Nitika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344782/
https://www.ncbi.nlm.nih.gov/pubmed/37414849
http://dx.doi.org/10.1038/s41556-023-01167-z

Ejemplares similares

Ejemplares similares