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A spatial genome aligner for resolving chromatin architectures from multiplexed DNA FISH

Multiplexed fluorescence in situ hybridization (FISH) is a widely used approach for analyzing three-dimensional genome organization, but it is challenging to derive chromosomal conformations from noisy fluorescence signals, and tracing chromatin is not straightforward. Here we report a spatial genom...

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Detalles Bibliográficos
Autores principales: Jia, Bojing Blair, Jussila, Adam, Kern, Colin, Zhu, Quan, Ren, Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344783/
https://www.ncbi.nlm.nih.gov/pubmed/36593410
http://dx.doi.org/10.1038/s41587-022-01568-9