Class 3 PI3K coactivates the circadian clock to promote rhythmic de novo purine synthesis

Metabolic demands fluctuate rhythmically and rely on coordination between the circadian clock and nutrient-sensing signalling pathways, yet mechanisms of their interaction remain not fully understood. Surprisingly, we find that class 3 phosphatidylinositol-3-kinase (PI3K), known best for its essenti...

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Detalles Bibliográficos
Autores principales: Alkhoury, Chantal, Henneman, Nathaniel F., Petrenko, Volodymyr, Shibayama, Yui, Segaloni, Arianna, Gadault, Alexis, Nemazanyy, Ivan, Le Guillou, Edouard, Wolide, Amare Desalegn, Antoniadou, Konstantina, Tong, Xin, Tamaru, Teruya, Ozawa, Takeaki, Girard, Muriel, Hnia, Karim, Lutter, Dominik, Dibner, Charna, Panasyuk, Ganna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344785/
https://www.ncbi.nlm.nih.gov/pubmed/37414850
http://dx.doi.org/10.1038/s41556-023-01171-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344785/
https://www.ncbi.nlm.nih.gov/pubmed/37414850
http://dx.doi.org/10.1038/s41556-023-01171-3

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