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Optimization and evaluation of Lisinopril mucoadhesive sustained release matrix pellets: In-vitro and ex-vivo studies

Lisinopril (LIS) is antihypertensive drug, classified as a class III drug with high water solubility and low permeability. To overcome the low permeability, 3(2) factorial designs aimed to formulate LIS as a sustained-release (LIS-SR) matrix pellet by extrusion/spheronization. Matrix pellets were co...

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Detalles Bibliográficos
Autores principales:	Alagili, Modhi F., AlQuadeib, Bushra T., Ashri, Lubna Y., Ibrahim, Mohamed Abbas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344808/ https://www.ncbi.nlm.nih.gov/pubmed/37457369 http://dx.doi.org/10.1016/j.jsps.2023.06.023

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