Short-term anti-TNF therapy with surgical closure versus anti-TNF therapy alone for Crohn's perianal fistulas (PISA-II): long-term outcomes of an international, multicentre patient preference, randomised controlled trial

BACKGROUND: The PISA-II trial showed that short-term anti-tumour necrosis factor (anti-TNF) therapy followed by surgical closure induces radiological healing of perianal fistulas in patients with Crohn's disease more frequently than anti-TNF therapy alone after 18 months. This study aimed to co...

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Detalles Bibliográficos
Autores principales: Meima - van Praag, Elise M., Becker, Marte A.J., van Rijn, Kyra L., Wasmann, Karin A.T.G.M., Stoker, Jaap, D'Haens, Geert R.A.M., Ponsioen, Cyriel Y., Gecse, Krisztina B., Dijkgraaf, Marcel G.W., Spinelli, Antonino, Danese, Silvio, Bemelman, Willem A., Buskens, Christianne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344824/
https://www.ncbi.nlm.nih.gov/pubmed/37457118
http://dx.doi.org/10.1016/j.eclinm.2023.102045

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