Liver lipophagy ameliorates nonalcoholic steatohepatitis through extracellular lipid secretion

Nonalcoholic steatohepatitis (NASH) is a progressive disorder with aberrant lipid accumulation and subsequent inflammatory and profibrotic response. Therapeutic efforts at lipid reduction via increasing cytoplasmic lipolysis unfortunately worsens hepatitis due to toxicity of liberated fatty acid. An...

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Detalles Bibliográficos
Autores principales: Minami, Yoshito, Hoshino, Atsushi, Higuchi, Yusuke, Hamaguchi, Masahide, Kaneko, Yusaku, Kirita, Yuhei, Taminishi, Shunta, Nishiji, Toshiyuki, Taruno, Akiyuki, Fukui, Michiaki, Arany, Zoltan, Matoba, Satoaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344867/
https://www.ncbi.nlm.nih.gov/pubmed/37443159
http://dx.doi.org/10.1038/s41467-023-39404-6

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