Cargando…

β‐arrestin 2 negatively regulates lung cancer progression by inhibiting the TRAF6 signaling axis for NF-κB activation and autophagy induced by TLR3 and TLR4

β‐arrestin 2 (ARRB2) is functionally implicated in cancer progression via various signaling pathways. However, its role in lung cancer remains unclear. To obtain clinical insight on its function in lung cancer, microarray data from lung tumor tissues (LTTs) and matched lung normal tissues (mLNTs) of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Ji Young, Shin, Ji Hye, Kim, Mi-Jeong, Kang, Yeeun, Lee, Ji Su, Son, Juhee, Jeong, Soo-Kyung, Kim, Daesik, Kim, Duk-Hwan, Chun, Eunyoung, Lee, Ki-Young
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344878/ https://www.ncbi.nlm.nih.gov/pubmed/37443143 http://dx.doi.org/10.1038/s41419-023-05945-3

Ejemplares similares

FFAR2 antagonizes TLR2- and TLR3-induced lung cancer progression via the inhibition of AMPK-TAK1 signaling axis for the activation of NF-κB
por: Kim, Mi-Jeong, et al.
Publicado: (2023)

USP8 regulates liver cancer progression via the inhibition of TRAF6-mediated signal for NF-κB activation and autophagy induction by TLR4
por: Kim, Mi-Jeong, et al.
Publicado: (2021)

AMPKα1 Regulates Lung and Breast Cancer Progression by Regulating TLR4-Mediated TRAF6-BECN1 Signaling Axis
por: Kim, Mi-Jeong, et al.
Publicado: (2020)

p62 is Negatively Implicated in the TRAF6-BECN1 Signaling Axis for Autophagy Activation and Cancer Progression by Toll-Like Receptor 4 (TLR4)
por: Kim, Mi-Jeong, et al.
Publicado: (2020)

USP15 negatively regulates lung cancer progression through the TRAF6-BECN1 signaling axis for autophagy induction
por: Kim, Mi-Jeong, et al.
Publicado: (2022)

Hepatitis B virus X Protein Promotes Liver Cancer Progression through Autophagy Induction in Response to TLR4 Stimulation
por: Son, Juhee, et al.
Publicado: (2021)

Stratifin (SFN) regulates lung cancer progression via nucleating the Vps34‐BECN1‐TRAF6 complex for autophagy induction
por: Kim, Ji Young, et al.
Publicado: (2022)

p62 Negatively Regulates TLR4 Signaling via Functional Regulation of the TRAF6-ECSIT Complex
por: Kim, Mi-Jeong, et al.
Publicado: (2019)

CRBN is downregulated in lung cancer and negatively regulates TLR2, 4 and 7 stimulation in lung cancer cells
por: Kim, Mi‐Jeong, et al.
Publicado: (2022)

C-Cbl negatively regulates TRAF6-mediated NF-κB activation by promoting K48-linked polyubiquitination of TRAF6
por: Jang, Hyun-Duk, et al.
Publicado: (2019)

Roles of TLR7 in Activation of NF-κB Signaling of Keratinocytes by Imiquimod
por: Li, Zheng Jun, et al.
Publicado: (2013)

Cereblon negatively regulates TLR4 signaling through the attenuation of ubiquitination of TRAF6
por: Min, Yoon, et al.
Publicado: (2016)

Naringenin attenuates inflammation and apoptosis of osteoarthritic chondrocytes via the TLR4/TRAF6/NF-κB pathway
por: Wang, Yan, et al.
Publicado: (2023)

Expression of TLR2, TLR4, and TLR9 in dermatomyositis and polymyositis
por: Kim, Geun-Tae, et al.
Publicado: (2009)

JQ1, a BET inhibitor, controls TLR4-induced IL-10 production in regulatory B cells by BRD4-NF-κB axis
por: Lee, Min Bum, et al.
Publicado: (2017)

Intestinal mucosal injury induced by obstructive jaundice is associated with activation of TLR4/TRAF6/NF-κB pathways
por: Tian, Xiaopeng, et al.
Publicado: (2019)

Grape seed proanthocyanidin extract ameliorates murine autoimmune arthritis through regulation of TLR4/MyD88/NF-κB signaling pathway
por: Kim, Sang-Hyon, et al.
Publicado: (2018)

2-O-Methylhonokiol Suppresses HCV Replication via TRAF6-Mediated NF-kB Activation
por: Jeong, Suyun, et al.
Publicado: (2021)

MicroRNA 322-5p reduced neuronal inflammation via the TLR4/TRAF6/NF-κB axis in a rat epilepsy model
por: Zhou, Qin, et al.
Publicado: (2022)

TLR7 agonist induced repression of hepatocellular carcinoma via the TLR7-IKK-NF-κB-IL6 signaling pathway
por: REN, XINGBIN, et al.
Publicado: (2016)

TLR5 Activation through NF-κB Is a Neuroprotective Mechanism of Postconditioning after Cerebral Ischemia in Mice
por: Jeong, Jaewon, et al.
Publicado: (2017)

TLR7 promotes skin inflammation via activating NFκB-mTORC1 axis in rosacea
por: Huang, Yaqun, et al.
Publicado: (2023)

Downregulation of Matriptase Inhibits Porphyromonas gingivalis Lipopolysaccharide-Induced Matrix Metalloproteinase-1 and Proinflammatory Cytokines by Suppressing the TLR4/NF-κB Signaling Pathways in Human Gingival Fibroblasts
por: Kim, Jeong-Mi, et al.
Publicado: (2022)

Ginseng Sprouts Attenuate Mortality and Systemic Inflammation by Modulating TLR4/NF-κB Signaling in an LPS-Induced Mouse Model of Sepsis
por: Hwang, Seung-Ju, et al.
Publicado: (2023)

Correction: Intestinal mucosal injury induced by obstructive jaundice is associated with activation of TLR4/TRAF6/NF-κB pathways
por: Tian, Xiaopeng, et al.
Publicado: (2019)

Importance of extra- and intracellular domains of TLR1 and TLR2 in NFκB signaling
por: Sandor, Frantisek, et al.
Publicado: (2003)

Anti-Inflammatory Effect of Auranofin on Palmitic Acid and LPS-Induced Inflammatory Response by Modulating TLR4 and NOX4-Mediated NF-κB Signaling Pathway in RAW264.7 Macrophages
por: Hwangbo, Hyun, et al.
Publicado: (2021)

Peroxiredoxin-6 Negatively Regulates Bactericidal Activity and NF-κB Activity by Interrupting TRAF6-ECSIT Complex
por: Min, Yoon, et al.
Publicado: (2017)

Crystal structure of TRAF1 TRAF domain and its implications in the TRAF1-mediated intracellular signaling pathway
por: Kim, Chang Min, et al.
Publicado: (2016)

TLR3/TRIF signalling pathway regulates IL-32 and IFN-β secretion through activation of RIP-1 and TRAF in the human cornea
por: Park, Ga Bin, et al.
Publicado: (2015)

Epigenetic modification of TLR4 promotes activation of NF-κB by regulating methyl-CpG-binding domain protein 2 and Sp1 in gastric cancer
por: Kim, Tae Woo, et al.
Publicado: (2015)

Phloretin as a Potent Natural TLR2/1 Inhibitor Suppresses TLR2-Induced Inflammation
por: Kim, Jieun, et al.
Publicado: (2018)

NF-κB, JNK, and TLR Signaling Pathways in Hepatocarcinogenesis
por: Maeda, Shin
Publicado: (2010)

Epigallocatechin-3-gallate rescues LPS-impaired adult hippocampal neurogenesis through suppressing the TLR4-NF-κB signaling pathway in mice
por: Seong, Kyung-Joo, et al.
Publicado: (2016)

A novel IRAK4/PIM1 inhibitor ameliorates rheumatoid arthritis and lymphoid malignancy by blocking the TLR/MYD88-mediated NF-κB pathway
por: Yoon, Sae-Bom, et al.
Publicado: (2023)

Hypothalamic TLR2 triggers sickness behavior via a microglia-neuronal axis
por: Jin, Sungho, et al.
Publicado: (2016)

β-arrestin 2 attenuates lipopolysaccharide-induced liver injury via inhibition of TLR4/NF-κB signaling pathway-mediated inflammation in mice
por: Jiang, Meng-Ping, et al.
Publicado: (2018)

Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue
por: ZHANG, JIAN-ZHENG, et al.
Publicado: (2014)

Mitochondrial DNA induces inflammation and increases TLR9/NF-κB expression in lung tissue
por: Zhang, Jian-Zheng, et al.
Publicado: (2023)

Transcriptome sequencing of microglial cells stimulated with TLR3 and TLR4 ligands
por: Das, Amitabh, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_jml2fv941bmc7cdfpt0dtcbmng