Effect of low-dose hydrocortisone and inhaled nitric oxide on inflammatory mediators and local pulmonary metalloproteinases activity in LPS-induced sepsis in piglets

Hospital mortality in sepsis varies between 30–45%. It has been shown that administration of inhaled nitric oxide (iNO) and intravenous corticosteroid in a porcine endotoxemia model attenuated the systemic inflammatory response. We explored the anti-inflammatory effect of a double-treatment strategy...

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Detalles Bibliográficos
Autores principales: Kiczak, Liliana, Pasławska, Urszula, Goździk, Waldemar, Adamik, Barbara, Zielińska, Marzena, Zieliński, Stanisław, Nowak, Kacper, Płóciennik, Michał, Bania, Jacek, Tabiś, Aleksandra, Nowak, Marcin, Pasławski, Robert, Frostell, Claes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344886/
https://www.ncbi.nlm.nih.gov/pubmed/37443327
http://dx.doi.org/10.1038/s41598-023-38311-6

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