The kynurenic acid analog SZR104 induces cytomorphological changes associated with the anti-inflammatory phenotype in cultured microglia

We previously showed the anti-inflammatory effects of kynurenic acid (KYNA) and its brain-penetrable analog N-(2-(dimethylamino)ethyl)-3-(morpholinomethyl)-4-hydroxyquinoline-2-carboxamide (SZR104) both in vivo and in vitro. Here, we identified the cytomorphological effects of KYNA and SZR104 in sec...

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Detalles Bibliográficos
Autores principales: Szabo, Melinda, Lajkó, Noémi, Dulka, Karolina, Barczánfalvi, Gábor, Lőrinczi, Bálint, Szatmári, István, Mihály, András, Vécsei, László, Gulya, Karoly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344911/
https://www.ncbi.nlm.nih.gov/pubmed/37443330
http://dx.doi.org/10.1038/s41598-023-38107-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344911/
https://www.ncbi.nlm.nih.gov/pubmed/37443330
http://dx.doi.org/10.1038/s41598-023-38107-8

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