Two distinct trajectories of clinical and neurodegeneration events in Parkinson’s disease

Increasing evidence suggests that Parkinson’s disease (PD) exhibits disparate spatial and temporal patterns of progression. Here we used a machine-learning technique—Subtype and Stage Inference (SuStaIn) — to uncover PD subtypes with distinct trajectories of clinical and neurodegeneration events. We...

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Detalles Bibliográficos
Autores principales: Zhou, Cheng, Wang, Linbo, Cheng, Wei, Lv, JinChao, Guan, Xiaoujun, Guo, Tao, Wu, Jingjing, Zhang, Wei, Gao, Ting, Liu, Xiaocao, Bai, Xueqin, Wu, Haoting, Cao, Zhengye, Gu, Luyan, Chen, Jingwen, Wen, Jiaqi, Huang, Peiyu, Xu, Xiaojun, Zhang, Baorong, Feng, Jianfeng, Zhang, Minming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344958/
https://www.ncbi.nlm.nih.gov/pubmed/37443179
http://dx.doi.org/10.1038/s41531-023-00556-3

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