Single cell RNA sequencing unravels mechanisms underlying senescence-like phenotypes of alveolar macrophages

Alveolar macrophages (AMs) are resident innate immune cells that play vital roles in maintaining lung physiological functions. However, the effects of aging on their dynamics, heterogeneity, and transcriptional profiles remain to be fully elucidated. Through single cell RNA sequencing (scRNA-seq), w...

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Detalles Bibliográficos
Autores principales: Wu, Yue, Hu, Shengen Shawn, Zhang, Ruixuan, Goplen, Nick P., Gao, Xiaochen, Narasimhan, Harish, Shi, Ao, Chen, Yin, Li, Ying, Zang, Chongzhi, Dong, Haidong, Braciale, Thomas J., Zhu, Bibo, Sun, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10344965/
https://www.ncbi.nlm.nih.gov/pubmed/37456831
http://dx.doi.org/10.1016/j.isci.2023.107197

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