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Genes associated with cognitive ability and HAR show overlapping expression patterns in human cortical neuron types

GWAS have identified numerous genes associated with human cognition but their cell type expression profiles in the human brain are unknown. These genes overlap with human accelerated regions (HARs) implicated in human brain evolution and might act on the same biological processes. Here, we investiga...

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Detalles Bibliográficos
Autores principales: Driessens, Stan L. W., Galakhova, Anna A., Heyer, Djai B., Pieterse, Isabel J., Wilbers, René, Mertens, Eline J., Waleboer, Femke, Heistek, Tim S., Coenen, Loet, Meijer, Julia R., Idema, Sander, de Witt Hamer, Philip C., Noske, David P., de Kock, Christiaan P. J., Lee, Brian R., Smith, Kimberly, Ting, Jonathan T., Lein, Ed S., Mansvelder, Huibert D., Goriounova, Natalia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345092/
https://www.ncbi.nlm.nih.gov/pubmed/37443107
http://dx.doi.org/10.1038/s41467-023-39946-9