Spatial and functional arrangement of Ebola virus polymerase inside phase-separated viral factories

Ebola virus (EBOV) infection induces the formation of membrane-less, cytoplasmic compartments termed viral factories, in which multiple viral proteins gather and coordinate viral transcription, replication, and assembly. Key to viral factory function is the recruitment of EBOV polymerase, a multifun...

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Detalles Bibliográficos
Autores principales: Fang, Jingru, Castillon, Guillaume, Phan, Sebastien, McArdle, Sara, Hariharan, Chitra, Adams, Aiyana, Ellisman, Mark H., Deniz, Ashok A., Saphire, Erica Ollmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345124/
https://www.ncbi.nlm.nih.gov/pubmed/37443171
http://dx.doi.org/10.1038/s41467-023-39821-7

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