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Impact of misclassified defective proviruses on HIV reservoir measurements

Most proviruses persisting in people living with HIV (PWH) on antiretroviral therapy (ART) are defective. However, rarer intact proviruses almost always reinitiate viral rebound if ART stops. Therefore, assessing therapies to prevent viral rebound hinges on specifically quantifying intact proviruses...

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Detalles Bibliográficos
Autores principales:	Reeves, Daniel B., Gaebler, Christian, Oliveira, Thiago Y., Peluso, Michael J., Schiffer, Joshua T., Cohn, Lillian B., Deeks, Steven G., Nussenzweig, Michel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345136/ https://www.ncbi.nlm.nih.gov/pubmed/37443365 http://dx.doi.org/10.1038/s41467-023-39837-z

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