Cargando…

Navigating the complex landscape of benzodiazepine- and Z-drug diversity: insights from comprehensive FDA adverse event reporting system analysis and beyond

INTRODUCTION: Medications which target benzodiazepine (BZD) binding sites of GABAA receptors (GABAARs) have been in widespread use since the nineteen-sixties. They carry labels as anxiolytics, hypnotics or antiepileptics. All benzodiazepines and several nonbenzodiazepine Z-drugs share high affinity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Koniuszewski, Filip, Vogel, Florian D., Dajić, Irena, Seidel, Thomas, Kunze, Markus, Willeit, Matthäus, Ernst, Margot
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Psychiatry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345211/ https://www.ncbi.nlm.nih.gov/pubmed/37457785 http://dx.doi.org/10.3389/fpsyt.2023.1188101

Ejemplares similares

Tricyclic antipsychotics and antidepressants can inhibit α5‐containing GABA(A) receptors by two distinct mechanisms
por: Bampali, Konstantina, et al.
Publicado: (2022)

Prevalence and correlates of the misuse of z-drugs and benzodiazepines in the National Survey on Drug Use and Health
por: McHugh, R. Kathryn, et al.
Publicado: (2023)

Cys-loop receptors on cannabinoids: All high?
por: Schmiedhofer, Philip, et al.
Publicado: (2022)

Structure-Guided Computational Methods Predict Multiple Distinct Binding Modes for Pyrazoloquinolinones in GABA(A) Receptors
por: Fabjan, Jure, et al.
Publicado: (2021)

Continuous Infusion of Flumazenil in the Management of Benzodiazepines Detoxification
por: Benini, Anna, et al.
Publicado: (2021)

Benzodiazepine Misuse: An Epidemic Within a Pandemic
por: Sarangi, Ashish, et al.
Publicado: (2021)

Editorial: Benzodiazepine addiction: from lab to street
por: Berro, Lais F., et al.
Publicado: (2023)

Comparisons Between Successful Versus Unsuccessful Switches From Benzodiazepines or Zolpidem (Z-Drug) to Controlled-Release Melatonin in Patients With Major Depressive Disorder and Insomnia
por: An, Ji Hyun, et al.
Publicado: (2020)

The Antidepressant Effect of Ketamine Is Dampened by Concomitant Benzodiazepine Medication
por: Andrashko, Veronika, et al.
Publicado: (2020)

Molecular Mingling: Multimodal Predictions of Ligand Promiscuity in Pentameric Ligand-Gated Ion Channels
por: Koniuszewski, Filip, et al.
Publicado: (2022)

Addiction of High Dose of Benzodiazepine: Verona Detox Approach With Flumazenil
por: Casari, Rebecca, et al.
Publicado: (2022)

Study protocol—Evoked craving in high-dose benzodiazepine users
por: Zamboni, Lorenzo, et al.
Publicado: (2022)

GABA(A) receptor subtypes and benzodiazepine use, misuse, and abuse
por: Engin, Elif
Publicado: (2023)

Benzodiazepines in sport, an underestimated problem: Recommendations for sports medicine physicians’ practice
por: Zandonai, Thomas, et al.
Publicado: (2022)

Predicting benzodiazepine prescriptions: A proof-of-concept machine learning approach
por: Kinney, Kerry L., et al.
Publicado: (2023)

Long-term use of benzodiazepines in chronic insomnia: a European perspective
por: Soyka, Michael, et al.
Publicado: (2023)

Concomitant medications associated with ischemic, hypertensive, and arrhythmic events in MDMA users in FDA adverse event reporting system
por: Makunts, Tigran, et al.
Publicado: (2023)

Commentary: Hypnotic Medications and Suicide: Risk, Mechanisms, Mitigation, and the FDA
por: Ruan, Xiulu, et al.
Publicado: (2017)

Anhedonia modulates benzodiazepine and opioid demand among persons in treatment for opioid use disorder
por: Greenwald, Mark K., et al.
Publicado: (2023)

Development and acceptability of a decision aid for anxiety disorder considering discontinuation of benzodiazepine anxiolytic
por: Aoki, Yumi, et al.
Publicado: (2023)

Is the Long-Term Use of Benzodiazepines Associated With Worse Cognition Performance in Highly Educated Older Adults?
por: Liu, Linzi, et al.
Publicado: (2020)

Cortical Glutamate and GABA Changes During Early Abstinence in Alcohol Dependence and Their Associations With Benzodiazepine Medication
por: Wang, Guoying, et al.
Publicado: (2021)

Case report: Interstitial pneumonitis after initiation of lamotrigine
por: Watzal, Victoria, et al.
Publicado: (2023)

The Effects of Benzodiazepine Use and Abuse on Cognition in the Elders: A Systematic Review and Meta-Analysis of Comparative Studies
por: Liu, Linzi, et al.
Publicado: (2020)

Transcranial random noise stimulation-induced plasticity is NMDA-receptor independent but sodium-channel blocker and benzodiazepines sensitive
por: Chaieb, Leila, et al.
Publicado: (2015)

Use of Benzodiazepines and Z-Drugs in Multiple Sclerosis
por: Marrie, Ruth Ann, et al.
Publicado: (2022)

Adverse childhood experiences as risk factors for recurrent admissions in young psychiatric inpatients
por: Fellinger, Matthäus, et al.
Publicado: (2022)

The FDA “Black Box” Warning on Antidepressant Suicide Risk in Young Adults: More Harm Than Benefits?
por: Fornaro, Michele, et al.
Publicado: (2019)

Maintenance Therapy of Psychosis Spectrum Disorders in a Real-World Setting: Antipsychotics Prescription Patterns and Long-Term Benzodiazepine Use
por: Maric, Nadja P., et al.
Publicado: (2022)

Editorial: Spatial Navigation and Neurodevelopmental Disorders
por: Faedda, Noemi, et al.
Publicado: (2022)

GABA(A) Receptor Ligands Often Interact with Binding Sites in the Transmembrane Domain and in the Extracellular Domain—Can the Promiscuity Code Be Cracked?
por: Iorio, Maria Teresa, et al.
Publicado: (2020)

Polysubstance Use Patterns Among High Dose Benzodiazepine Users: A Latent Class Analysis and Differences Between Male and Female Use
por: Zamboni, Lorenzo, et al.
Publicado: (2022)

Timing of antipsychotics and benzodiazepine initiation during a first episode of psychosis impacts clinical outcomes: Electronic health record cohort study
por: Arribas, Maite, et al.
Publicado: (2022)

Deep Brain Stimulation for Obsessive-Compulsive Disorder: Real World Experience Post-FDA-Humanitarian Use Device Approval
por: Kahn, Lora, et al.
Publicado: (2021)

Benzodiazepine and Z-Drug Use and the Risk of Developing Dementia
por: Torres-Bondia, Francisco, et al.
Publicado: (2021)

Benzodiazepines and Z-Drugs: An Updated Review of Major Adverse Outcomes Reported on in Epidemiologic Research
por: Brandt, Jaden, et al.
Publicado: (2017)

Case Report: The Role of Neuropsychological Assessment and Imaging Biomarkers in the Early Diagnosis of Lewy Body Dementia in a Patient With Major Depression and Prolonged Alcohol and Benzodiazepine Dependence
por: Bouter, Caroline, et al.
Publicado: (2020)

The current landscape of the FDA approved companion diagnostics
por: Jørgensen, Jan Trøst
Publicado: (2021)

Drugs Interfering with Muscarinic Acetylcholine Receptors and Their Effects on Place Navigation
por: Svoboda, Jan, et al.
Publicado: (2017)

Adult attention-deficit/hyperactivity disorder symptoms, cognitive dysfunction and quality of life in high-dose use of benzodiazepine and Z-drug
por: Federico, Angela, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_l0kekr7dlavl51gt9gcto1fu1t