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Apremilast ameliorates acute respiratory distress syndrome by inhibiting neutrophil-induced oxidative stress

BACKGROUND: The pathogenesis of acute respiratory distress syndrome (ARDS) is attributed to the dysregulation of oxidative stress and neutrophil recruitment. We aimed to investigate the anti-inflammatory effects of apremilast on human neutrophils and assess its efficacy for treating ARDS. METHODS: W...

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Detalles Bibliográficos
Autores principales: Tsai, Yung-Fong, Chen, Chun-Yu, Yang, Shun-Chin, Syu, Yu-Ting, Hwang, Tsong-Long
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chang Gung University 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345255/
https://www.ncbi.nlm.nih.gov/pubmed/36103985
http://dx.doi.org/10.1016/j.bj.2022.09.001

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