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A Rare Case of Opsoclonus Myoclonus Ataxia Syndrome Post Viral Illness

Opsoclonus myoclonus ataxia syndrome (OMAS) is a rare inflammatory neurological disorder characterized by ocular, motor, behavioral, language, and sleep disturbances. It usually affects infants and young children but may affect adults. A 28-year-old male was brought to our emergency ward with compla...

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Autores principales: Shah, Nauka S, Pathak, Jaya, Shah, Purva C, Bharmal, Ummayhany F, Ansari, Maliha I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345879/
https://www.ncbi.nlm.nih.gov/pubmed/37456490
http://dx.doi.org/10.7759/cureus.40396
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author Shah, Nauka S
Pathak, Jaya
Shah, Purva C
Bharmal, Ummayhany F
Ansari, Maliha I
author_facet Shah, Nauka S
Pathak, Jaya
Shah, Purva C
Bharmal, Ummayhany F
Ansari, Maliha I
author_sort Shah, Nauka S
collection PubMed
description Opsoclonus myoclonus ataxia syndrome (OMAS) is a rare inflammatory neurological disorder characterized by ocular, motor, behavioral, language, and sleep disturbances. It usually affects infants and young children but may affect adults. A 28-year-old male was brought to our emergency ward with complaints of involuntary spontaneous eye movements and jerky movements of limbs with imbalance while walking. He had a history of short febrile illness 10 days prior. His magnetic resonance imaging (MRI) of the brain, cerebrospinal fluid (CSF) analysis, and other routine investigations were normal. The patient was treated with injectable methylprednisolone (1 g) given for five days along with other supportive therapy. A significant reduction in the opsoclonus, myoclonus, and ataxia was seen on a six-month follow-up. OMAS should be identified early to avoid the use of inappropriate medications, and immunotherapy must be provided as early as possible in order to prevent irreversible neurological damage.
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spelling pubmed-103458792023-07-15 A Rare Case of Opsoclonus Myoclonus Ataxia Syndrome Post Viral Illness Shah, Nauka S Pathak, Jaya Shah, Purva C Bharmal, Ummayhany F Ansari, Maliha I Cureus Internal Medicine Opsoclonus myoclonus ataxia syndrome (OMAS) is a rare inflammatory neurological disorder characterized by ocular, motor, behavioral, language, and sleep disturbances. It usually affects infants and young children but may affect adults. A 28-year-old male was brought to our emergency ward with complaints of involuntary spontaneous eye movements and jerky movements of limbs with imbalance while walking. He had a history of short febrile illness 10 days prior. His magnetic resonance imaging (MRI) of the brain, cerebrospinal fluid (CSF) analysis, and other routine investigations were normal. The patient was treated with injectable methylprednisolone (1 g) given for five days along with other supportive therapy. A significant reduction in the opsoclonus, myoclonus, and ataxia was seen on a six-month follow-up. OMAS should be identified early to avoid the use of inappropriate medications, and immunotherapy must be provided as early as possible in order to prevent irreversible neurological damage. Cureus 2023-06-14 /pmc/articles/PMC10345879/ /pubmed/37456490 http://dx.doi.org/10.7759/cureus.40396 Text en Copyright © 2023, Shah et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Shah, Nauka S
Pathak, Jaya
Shah, Purva C
Bharmal, Ummayhany F
Ansari, Maliha I
A Rare Case of Opsoclonus Myoclonus Ataxia Syndrome Post Viral Illness
title A Rare Case of Opsoclonus Myoclonus Ataxia Syndrome Post Viral Illness
title_full A Rare Case of Opsoclonus Myoclonus Ataxia Syndrome Post Viral Illness
title_fullStr A Rare Case of Opsoclonus Myoclonus Ataxia Syndrome Post Viral Illness
title_full_unstemmed A Rare Case of Opsoclonus Myoclonus Ataxia Syndrome Post Viral Illness
title_short A Rare Case of Opsoclonus Myoclonus Ataxia Syndrome Post Viral Illness
title_sort rare case of opsoclonus myoclonus ataxia syndrome post viral illness
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345879/
https://www.ncbi.nlm.nih.gov/pubmed/37456490
http://dx.doi.org/10.7759/cureus.40396
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