Resolving the Pathogenesis of Anaplastic Wilms Tumors through Spatial Mapping of Cancer Cell Evolution

PURPOSE: While patients with intermediate-risk (IR) Wilms tumors now have an overall survival (OS) rate of almost 90%, those affected by high-stage tumors with diffuse anaplasia have an OS of only around 50%. We here identify key events in the pathogenesis of diffuse anaplasia by mapping cancer cell...

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Detalles Bibliográficos
Autores principales: Rastegar, Bahar, Andersson, Natalie, Petersson, Alexandra, Karlsson, Jenny, Chattopadhyay, Subhayan, Valind, Anders, Jansson, Caroline, Durand, Geoffroy, Romerius, Patrik, Jirström, Karin, Holmquist Mengelbier, Linda, Gisselsson, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345961/
https://www.ncbi.nlm.nih.gov/pubmed/37140929
http://dx.doi.org/10.1158/1078-0432.CCR-23-0311

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