A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2–Bispecific Antibody for Combination Cancer Therapy

PURPOSE: Accumulating analyses of pro-oncogenic molecular mechanisms triggered a rapid development of targeted cancer therapies. Although many of these treatments produce impressive initial responses, eventual resistance onset is practically unavoidable. One of the main approaches for preventing thi...

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Detalles Bibliográficos
Autores principales: El Zawily, Amr, Vizeacoumar, Frederick S., Dahiya, Renuka, Banerjee, Sara L., Bhanumathy, Kalpana K., Elhasasna, Hussain, Hanover, Glinton, Sharpe, Jessica C., Sanchez, Malkon G., Greidanus, Paul, Stacey, R. Greg, Moon, Kyung-Mee, Alexandrov, Ilya, Himanen, Juha P., Nikolov, Dimitar B., Fonge, Humphrey, White, Aaron P., Foster, Leonard J., Wang, Bingcheng, Toosi, Behzad M., Bisson, Nicolas, Mirzabekov, Tajib A., Vizeacoumar, Franco J., Freywald, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Translational Cancer Mechanisms and Therapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345963/
https://www.ncbi.nlm.nih.gov/pubmed/36976175
http://dx.doi.org/10.1158/1078-0432.CCR-22-2535

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