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TIGIT Expression Delineates T-cell Populations with Distinct Functional and Prognostic Impact in Pancreatic Cancer

PURPOSE: Immunotherapy has led to a fundamental shift in the treatment of several cancers. However, its efficacy in pancreatic ductal adenocarcinoma (PDAC) is limited. Understanding the expression of inhibitory immune checkpoint receptors (ICR) by intratumoral T cells may help to unravel their invol...

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Detalles Bibliográficos
Autores principales:	Heiduk, Max, Klimova, Anna, Reiche, Charlotte, Digomann, David, Beer, Carolin, Aust, Daniela E., Distler, Marius, Weitz, Jürgen, Seifert, Adrian M., Seifert, Lena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2023
Materias:	Translational Cancer Mechanisms and Therapy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345964/ https://www.ncbi.nlm.nih.gov/pubmed/37140899 http://dx.doi.org/10.1158/1078-0432.CCR-23-0258

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