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Human Olfactory Receptor Sensor for Odor Reconstitution

Among the five human senses, light, sound, and force perceived by the eye, ear, and skin, respectively are physical phenomena, and therefore can be easily measured and expressed as objective, univocal, and simple digital data with physical quantity. However, as taste and odor molecules perceived by...

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Autores principales: Kuroda, Shun’ichi, Nakaya-Kishi, Yukiko, Tatematsu, Kenji, Hinuma, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346456/
https://www.ncbi.nlm.nih.gov/pubmed/37448013
http://dx.doi.org/10.3390/s23136164
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author Kuroda, Shun’ichi
Nakaya-Kishi, Yukiko
Tatematsu, Kenji
Hinuma, Shuji
author_facet Kuroda, Shun’ichi
Nakaya-Kishi, Yukiko
Tatematsu, Kenji
Hinuma, Shuji
author_sort Kuroda, Shun’ichi
collection PubMed
description Among the five human senses, light, sound, and force perceived by the eye, ear, and skin, respectively are physical phenomena, and therefore can be easily measured and expressed as objective, univocal, and simple digital data with physical quantity. However, as taste and odor molecules perceived by the tongue and nose are chemical phenomena, it has been difficult to express them as objective and univocal digital data, since no reference chemicals can be defined. Therefore, while the recording, saving, transmitting to remote locations, and replaying of human visual, auditory, and tactile information as digital data in digital devices have been realized (this series of data flow is defined as DX (digital transformation) in this review), the DX of human taste and odor information is not yet in the realization stage. Particularly, since there are at least 400,000 types of odor molecules and an infinite number of complex odors that are mixtures of these molecules, it has been considered extremely difficult to realize “human olfactory DX” by converting all odors perceived by human olfaction into digital data. In this review, we discuss the current status and future prospects of the development of “human olfactory DX”, which we believe can be realized by utilizing odor sensors that employ the olfactory receptors (ORs) that support human olfaction as sensing molecules (i.e., human OR sensor).
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spelling pubmed-103464562023-07-15 Human Olfactory Receptor Sensor for Odor Reconstitution Kuroda, Shun’ichi Nakaya-Kishi, Yukiko Tatematsu, Kenji Hinuma, Shuji Sensors (Basel) Review Among the five human senses, light, sound, and force perceived by the eye, ear, and skin, respectively are physical phenomena, and therefore can be easily measured and expressed as objective, univocal, and simple digital data with physical quantity. However, as taste and odor molecules perceived by the tongue and nose are chemical phenomena, it has been difficult to express them as objective and univocal digital data, since no reference chemicals can be defined. Therefore, while the recording, saving, transmitting to remote locations, and replaying of human visual, auditory, and tactile information as digital data in digital devices have been realized (this series of data flow is defined as DX (digital transformation) in this review), the DX of human taste and odor information is not yet in the realization stage. Particularly, since there are at least 400,000 types of odor molecules and an infinite number of complex odors that are mixtures of these molecules, it has been considered extremely difficult to realize “human olfactory DX” by converting all odors perceived by human olfaction into digital data. In this review, we discuss the current status and future prospects of the development of “human olfactory DX”, which we believe can be realized by utilizing odor sensors that employ the olfactory receptors (ORs) that support human olfaction as sensing molecules (i.e., human OR sensor). MDPI 2023-07-05 /pmc/articles/PMC10346456/ /pubmed/37448013 http://dx.doi.org/10.3390/s23136164 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kuroda, Shun’ichi
Nakaya-Kishi, Yukiko
Tatematsu, Kenji
Hinuma, Shuji
Human Olfactory Receptor Sensor for Odor Reconstitution
title Human Olfactory Receptor Sensor for Odor Reconstitution
title_full Human Olfactory Receptor Sensor for Odor Reconstitution
title_fullStr Human Olfactory Receptor Sensor for Odor Reconstitution
title_full_unstemmed Human Olfactory Receptor Sensor for Odor Reconstitution
title_short Human Olfactory Receptor Sensor for Odor Reconstitution
title_sort human olfactory receptor sensor for odor reconstitution
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346456/
https://www.ncbi.nlm.nih.gov/pubmed/37448013
http://dx.doi.org/10.3390/s23136164
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