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Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review

The consumption of foods that are rich in phenolic compounds has chemopreventive effects on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide spectrum of their health-promoting properties such as antioxidant, anti-inflammatory, and anticancer activities, has been...

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Autores principales: Wendlocha, Dominika, Krzykawski, Kamil, Mielczarek-Palacz, Aleksandra, Kubina, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346890/
https://www.ncbi.nlm.nih.gov/pubmed/37447264
http://dx.doi.org/10.3390/nu15132938
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author Wendlocha, Dominika
Krzykawski, Kamil
Mielczarek-Palacz, Aleksandra
Kubina, Robert
author_facet Wendlocha, Dominika
Krzykawski, Kamil
Mielczarek-Palacz, Aleksandra
Kubina, Robert
author_sort Wendlocha, Dominika
collection PubMed
description The consumption of foods that are rich in phenolic compounds has chemopreventive effects on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide spectrum of their health-promoting properties such as antioxidant, anti-inflammatory, and anticancer activities, has been demonstrated. This paper analyzes the mechanisms of the anticancer action of selected common flavonols, including kemferol, myricetin, quercetin, fisetin, galangin, isorhamnetin, and morin, in preclinical studies, with particular emphasis on in vitro studies in gynecological cancers and breast cancer. In the future, these compounds may find applications in the prevention and treatment of gynecological cancers and breast cancer, but this requires further, more advanced research.
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spelling pubmed-103468902023-07-15 Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review Wendlocha, Dominika Krzykawski, Kamil Mielczarek-Palacz, Aleksandra Kubina, Robert Nutrients Review The consumption of foods that are rich in phenolic compounds has chemopreventive effects on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide spectrum of their health-promoting properties such as antioxidant, anti-inflammatory, and anticancer activities, has been demonstrated. This paper analyzes the mechanisms of the anticancer action of selected common flavonols, including kemferol, myricetin, quercetin, fisetin, galangin, isorhamnetin, and morin, in preclinical studies, with particular emphasis on in vitro studies in gynecological cancers and breast cancer. In the future, these compounds may find applications in the prevention and treatment of gynecological cancers and breast cancer, but this requires further, more advanced research. MDPI 2023-06-28 /pmc/articles/PMC10346890/ /pubmed/37447264 http://dx.doi.org/10.3390/nu15132938 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Wendlocha, Dominika
Krzykawski, Kamil
Mielczarek-Palacz, Aleksandra
Kubina, Robert
Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review
title Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review
title_full Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review
title_fullStr Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review
title_full_unstemmed Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review
title_short Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review
title_sort selected flavonols in breast and gynecological cancer: a systematic review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346890/
https://www.ncbi.nlm.nih.gov/pubmed/37447264
http://dx.doi.org/10.3390/nu15132938
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