Cargando…
Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review
The consumption of foods that are rich in phenolic compounds has chemopreventive effects on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide spectrum of their health-promoting properties such as antioxidant, anti-inflammatory, and anticancer activities, has been...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346890/ https://www.ncbi.nlm.nih.gov/pubmed/37447264 http://dx.doi.org/10.3390/nu15132938 |
_version_ | 1785073420629704704 |
---|---|
author | Wendlocha, Dominika Krzykawski, Kamil Mielczarek-Palacz, Aleksandra Kubina, Robert |
author_facet | Wendlocha, Dominika Krzykawski, Kamil Mielczarek-Palacz, Aleksandra Kubina, Robert |
author_sort | Wendlocha, Dominika |
collection | PubMed |
description | The consumption of foods that are rich in phenolic compounds has chemopreventive effects on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide spectrum of their health-promoting properties such as antioxidant, anti-inflammatory, and anticancer activities, has been demonstrated. This paper analyzes the mechanisms of the anticancer action of selected common flavonols, including kemferol, myricetin, quercetin, fisetin, galangin, isorhamnetin, and morin, in preclinical studies, with particular emphasis on in vitro studies in gynecological cancers and breast cancer. In the future, these compounds may find applications in the prevention and treatment of gynecological cancers and breast cancer, but this requires further, more advanced research. |
format | Online Article Text |
id | pubmed-10346890 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-103468902023-07-15 Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review Wendlocha, Dominika Krzykawski, Kamil Mielczarek-Palacz, Aleksandra Kubina, Robert Nutrients Review The consumption of foods that are rich in phenolic compounds has chemopreventive effects on many cancers, including breast cancer, ovarian cancer, and endometrial cancer. A wide spectrum of their health-promoting properties such as antioxidant, anti-inflammatory, and anticancer activities, has been demonstrated. This paper analyzes the mechanisms of the anticancer action of selected common flavonols, including kemferol, myricetin, quercetin, fisetin, galangin, isorhamnetin, and morin, in preclinical studies, with particular emphasis on in vitro studies in gynecological cancers and breast cancer. In the future, these compounds may find applications in the prevention and treatment of gynecological cancers and breast cancer, but this requires further, more advanced research. MDPI 2023-06-28 /pmc/articles/PMC10346890/ /pubmed/37447264 http://dx.doi.org/10.3390/nu15132938 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Wendlocha, Dominika Krzykawski, Kamil Mielczarek-Palacz, Aleksandra Kubina, Robert Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review |
title | Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review |
title_full | Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review |
title_fullStr | Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review |
title_full_unstemmed | Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review |
title_short | Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review |
title_sort | selected flavonols in breast and gynecological cancer: a systematic review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346890/ https://www.ncbi.nlm.nih.gov/pubmed/37447264 http://dx.doi.org/10.3390/nu15132938 |
work_keys_str_mv | AT wendlochadominika selectedflavonolsinbreastandgynecologicalcancerasystematicreview AT krzykawskikamil selectedflavonolsinbreastandgynecologicalcancerasystematicreview AT mielczarekpalaczaleksandra selectedflavonolsinbreastandgynecologicalcancerasystematicreview AT kubinarobert selectedflavonolsinbreastandgynecologicalcancerasystematicreview |