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Wound Healing Effect of Supercritical Carbon Dioxide Datura metel L. Leaves Extracts: An In Vitro Study of Anti-Inflammation, Cell Migration, MMP-2 Inhibition, and the Modulation of the Sonic Hedgehog Pathway in Human Fibroblasts
Datura metel L. (thorn apple) has been used in Thai folk wisdom for wound care. In this study, we chose supercritical carbon dioxide extraction (scCO(2)) to develop crude extraction from the leaves of the thorn apple. The phytochemical profiles were observed using liquid chromatography–quadrupole ti...
Autores principales: | Ruksiriwanich, Warintorn, Linsaenkart, Pichchapa, Muangsanguan, Anurak, Sringarm, Korawan, Jantrawut, Pensak, Arjin, Chaiwat, Sommano, Sarana Rose, Phimolsiripol, Yuthana, Barba, Francisco J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10346957/ https://www.ncbi.nlm.nih.gov/pubmed/37447107 http://dx.doi.org/10.3390/plants12132546 |
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