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Preoperative CT-guided localization of pulmonary nodules with low-dose radiation

BACKGROUND: Video-assisted thoracoscopic surgery (VATS) has been widely accepted for the treatment of pulmonary nodules. Prior to VATS, pulmonary nodules can be labeled by computed tomography (CT)-guided hook wire localization, but multiple scans are required, which increases the total radiation dos...

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Autores principales: Ma, Yanhe, Cheng, Shizhao, Li, Jianhui, Yuan, Wei, Song, Zhenchun, Zhang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347347/
https://www.ncbi.nlm.nih.gov/pubmed/37456304
http://dx.doi.org/10.21037/qims-22-1362
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author Ma, Yanhe
Cheng, Shizhao
Li, Jianhui
Yuan, Wei
Song, Zhenchun
Zhang, Hong
author_facet Ma, Yanhe
Cheng, Shizhao
Li, Jianhui
Yuan, Wei
Song, Zhenchun
Zhang, Hong
author_sort Ma, Yanhe
collection PubMed
description BACKGROUND: Video-assisted thoracoscopic surgery (VATS) has been widely accepted for the treatment of pulmonary nodules. Prior to VATS, pulmonary nodules can be labeled by computed tomography (CT)-guided hook wire localization, but multiple scans are required, which increases the total radiation dose. We aimed to assess the effectiveness and risks of using low-dose radiation CT to locate lung nodules prior to VATS. METHODS: This study included 158 patients who underwent VATS resection after CT-guided hook wire localization. Based on the CT tube voltage, patients were split into two groups: the low-voltage group (Group A) received 80 kV, while the high-voltage group (Group B) received 120 kV. The two groups’ image quality, radiation exposure, localization success and complication rates were compared. The frequencies of intraoperative complications and the types of lung nodules were also compared between the groups. RESULTS: Successful nodule mapping was obtained in 158 patients. There was no significant difference in age, sex ratio or BMI between the two groups. Subjective imaging quality in both groups met the requirements for location (≥2 points). The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in Group A were lower than those in Group B (P<0.05). Furthermore, the dose length product (DLP) and effective dose (ED) in Group A were lower than those in Group B (P<0.05). CONCLUSIONS: Low-dose radiation CT-guided localization is safe and feasible for identifying uncertain pulmonary nodules before VATS, enabling a significant radiation dose reduction while maintaining mapping accuracy and not increasing complication risk.
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spelling pubmed-103473472023-07-15 Preoperative CT-guided localization of pulmonary nodules with low-dose radiation Ma, Yanhe Cheng, Shizhao Li, Jianhui Yuan, Wei Song, Zhenchun Zhang, Hong Quant Imaging Med Surg Original Article BACKGROUND: Video-assisted thoracoscopic surgery (VATS) has been widely accepted for the treatment of pulmonary nodules. Prior to VATS, pulmonary nodules can be labeled by computed tomography (CT)-guided hook wire localization, but multiple scans are required, which increases the total radiation dose. We aimed to assess the effectiveness and risks of using low-dose radiation CT to locate lung nodules prior to VATS. METHODS: This study included 158 patients who underwent VATS resection after CT-guided hook wire localization. Based on the CT tube voltage, patients were split into two groups: the low-voltage group (Group A) received 80 kV, while the high-voltage group (Group B) received 120 kV. The two groups’ image quality, radiation exposure, localization success and complication rates were compared. The frequencies of intraoperative complications and the types of lung nodules were also compared between the groups. RESULTS: Successful nodule mapping was obtained in 158 patients. There was no significant difference in age, sex ratio or BMI between the two groups. Subjective imaging quality in both groups met the requirements for location (≥2 points). The signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) in Group A were lower than those in Group B (P<0.05). Furthermore, the dose length product (DLP) and effective dose (ED) in Group A were lower than those in Group B (P<0.05). CONCLUSIONS: Low-dose radiation CT-guided localization is safe and feasible for identifying uncertain pulmonary nodules before VATS, enabling a significant radiation dose reduction while maintaining mapping accuracy and not increasing complication risk. AME Publishing Company 2023-05-11 2023-07-01 /pmc/articles/PMC10347347/ /pubmed/37456304 http://dx.doi.org/10.21037/qims-22-1362 Text en 2023 Quantitative Imaging in Medicine and Surgery. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Ma, Yanhe
Cheng, Shizhao
Li, Jianhui
Yuan, Wei
Song, Zhenchun
Zhang, Hong
Preoperative CT-guided localization of pulmonary nodules with low-dose radiation
title Preoperative CT-guided localization of pulmonary nodules with low-dose radiation
title_full Preoperative CT-guided localization of pulmonary nodules with low-dose radiation
title_fullStr Preoperative CT-guided localization of pulmonary nodules with low-dose radiation
title_full_unstemmed Preoperative CT-guided localization of pulmonary nodules with low-dose radiation
title_short Preoperative CT-guided localization of pulmonary nodules with low-dose radiation
title_sort preoperative ct-guided localization of pulmonary nodules with low-dose radiation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347347/
https://www.ncbi.nlm.nih.gov/pubmed/37456304
http://dx.doi.org/10.21037/qims-22-1362
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