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Cubic Mesocrystal Magnetic Iron Oxide Nanoparticle Formation by Oriented Aggregation of Cubes in Organic Media: A Rational Design to Enhance the Magnetic Hyperthermia Efficiency
[Image: see text] Magnetic iron oxide mesocrystals have been reported to exhibit collective magnetic properties and consequently enhanced heating capabilities under alternating magnetic fields. However, there is no universal mechanism to fully explain the formation pathway that determines the partic...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347427/ https://www.ncbi.nlm.nih.gov/pubmed/37390112 http://dx.doi.org/10.1021/acsami.3c03254 |
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author | Egea-Benavente, David Díaz-Ufano, Carlos Gallo-Cordova, Álvaro Palomares, Francisco Javier Cuya Huaman, Jhon Lehman Barber, Domingo F. Morales, María del Puerto Balachandran, Jeyadevan |
author_facet | Egea-Benavente, David Díaz-Ufano, Carlos Gallo-Cordova, Álvaro Palomares, Francisco Javier Cuya Huaman, Jhon Lehman Barber, Domingo F. Morales, María del Puerto Balachandran, Jeyadevan |
author_sort | Egea-Benavente, David |
collection | PubMed |
description | [Image: see text] Magnetic iron oxide mesocrystals have been reported to exhibit collective magnetic properties and consequently enhanced heating capabilities under alternating magnetic fields. However, there is no universal mechanism to fully explain the formation pathway that determines the particle diameter, crystal size, and shape of these mesocrystals and their evolution along with the reaction. In this work, we have analyzed the formation of cubic magnetic iron oxide mesocrystals by thermal decomposition in organic media. We have observed that a nonclassical pathway leads to mesocrystals via the attachment of crystallographically aligned primary cubic particles and grows through sintering with time to achieve a sizable single crystal. In this case, the solvent 1-octadecene and the surfactant agent biphenyl-4-carboxylic acid seem to be the key parameters to form cubic mesocrystals as intermediates of the reaction in the presence of oleic acid. Interestingly, the magnetic properties and hyperthermia efficiency of the aqueous suspensions strongly depend on the degree of aggregation of the cores forming the final particle. The highest saturation magnetization and specific absorption rate values were found for the less aggregated mesocrystals. Thus, these cubic magnetic iron oxide mesocrystals stand out as an excellent alternative for biomedical applications with their enhanced magnetic properties. |
format | Online Article Text |
id | pubmed-10347427 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | American Chemical Society |
record_format | MEDLINE/PubMed |
spelling | pubmed-103474272023-07-15 Cubic Mesocrystal Magnetic Iron Oxide Nanoparticle Formation by Oriented Aggregation of Cubes in Organic Media: A Rational Design to Enhance the Magnetic Hyperthermia Efficiency Egea-Benavente, David Díaz-Ufano, Carlos Gallo-Cordova, Álvaro Palomares, Francisco Javier Cuya Huaman, Jhon Lehman Barber, Domingo F. Morales, María del Puerto Balachandran, Jeyadevan ACS Appl Mater Interfaces [Image: see text] Magnetic iron oxide mesocrystals have been reported to exhibit collective magnetic properties and consequently enhanced heating capabilities under alternating magnetic fields. However, there is no universal mechanism to fully explain the formation pathway that determines the particle diameter, crystal size, and shape of these mesocrystals and their evolution along with the reaction. In this work, we have analyzed the formation of cubic magnetic iron oxide mesocrystals by thermal decomposition in organic media. We have observed that a nonclassical pathway leads to mesocrystals via the attachment of crystallographically aligned primary cubic particles and grows through sintering with time to achieve a sizable single crystal. In this case, the solvent 1-octadecene and the surfactant agent biphenyl-4-carboxylic acid seem to be the key parameters to form cubic mesocrystals as intermediates of the reaction in the presence of oleic acid. Interestingly, the magnetic properties and hyperthermia efficiency of the aqueous suspensions strongly depend on the degree of aggregation of the cores forming the final particle. The highest saturation magnetization and specific absorption rate values were found for the less aggregated mesocrystals. Thus, these cubic magnetic iron oxide mesocrystals stand out as an excellent alternative for biomedical applications with their enhanced magnetic properties. American Chemical Society 2023-06-30 /pmc/articles/PMC10347427/ /pubmed/37390112 http://dx.doi.org/10.1021/acsami.3c03254 Text en © 2023 The Authors. Published by American Chemical Society https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Egea-Benavente, David Díaz-Ufano, Carlos Gallo-Cordova, Álvaro Palomares, Francisco Javier Cuya Huaman, Jhon Lehman Barber, Domingo F. Morales, María del Puerto Balachandran, Jeyadevan Cubic Mesocrystal Magnetic Iron Oxide Nanoparticle Formation by Oriented Aggregation of Cubes in Organic Media: A Rational Design to Enhance the Magnetic Hyperthermia Efficiency |
title | Cubic
Mesocrystal
Magnetic Iron Oxide Nanoparticle
Formation by Oriented Aggregation of Cubes in Organic Media: A Rational
Design to Enhance the Magnetic Hyperthermia Efficiency |
title_full | Cubic
Mesocrystal
Magnetic Iron Oxide Nanoparticle
Formation by Oriented Aggregation of Cubes in Organic Media: A Rational
Design to Enhance the Magnetic Hyperthermia Efficiency |
title_fullStr | Cubic
Mesocrystal
Magnetic Iron Oxide Nanoparticle
Formation by Oriented Aggregation of Cubes in Organic Media: A Rational
Design to Enhance the Magnetic Hyperthermia Efficiency |
title_full_unstemmed | Cubic
Mesocrystal
Magnetic Iron Oxide Nanoparticle
Formation by Oriented Aggregation of Cubes in Organic Media: A Rational
Design to Enhance the Magnetic Hyperthermia Efficiency |
title_short | Cubic
Mesocrystal
Magnetic Iron Oxide Nanoparticle
Formation by Oriented Aggregation of Cubes in Organic Media: A Rational
Design to Enhance the Magnetic Hyperthermia Efficiency |
title_sort | cubic
mesocrystal
magnetic iron oxide nanoparticle
formation by oriented aggregation of cubes in organic media: a rational
design to enhance the magnetic hyperthermia efficiency |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347427/ https://www.ncbi.nlm.nih.gov/pubmed/37390112 http://dx.doi.org/10.1021/acsami.3c03254 |
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