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Rapid Access to 2,2-Disubstituted Indolines via Dearomative Indolic-Claisen Rearrangement: Concise, Enantioselective Total Synthesis of (+)-Hinckdentine A

[Image: see text] The construction of 2,2-disubstituted indolines has long presented a synthetic challenge without any general solutions. Herein, we report a robust protocol for the dearomative Meerwein–Eschenmoser–Claisen rearrangement of 3-indolyl alcohols that provides efficient access to 2-subst...

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Detalles Bibliográficos
Autores principales: Baidilov, Daler, Elkin, Pavel K., Athe, Sudhakar, Rawal, Viresh H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347551/
https://www.ncbi.nlm.nih.gov/pubmed/37364288
http://dx.doi.org/10.1021/jacs.3c03611

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