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Atypical cholangiocytes derived from hepatocyte-cholangiocyte transdifferentiation mediated by COX-2: a kind of misguided liver regeneration

BACKGROUND: Hepatocyte-cholangiocyte transdifferentiation (HCT) is a potential origin of proliferating cholangiocytes in liver regeneration after chronic injury. This study aimed to determine HCT after chronic liver injury, verify the impacts of HCT on liver repair, and avoid harmful regeneration by...

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Detalles Bibliográficos
Autores principales: Lan, Tian, Tai, Yang, Zhao, Chong, Xiao, Yang, Yang, Zhu, Zhang, Linhao, Gan, Can, Dai, Wenting, Tong, Huan, Tang, Chengwei, Huang, Zhiyin, Gao, Jinhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347763/
https://www.ncbi.nlm.nih.gov/pubmed/37452426
http://dx.doi.org/10.1186/s41232-023-00284-4