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PARP inhibitor exerts an anti-tumor effect via LMO2 and synergizes with cisplatin in natural killer/T cell lymphoma
BACKGROUND: PARP inhibitor (PARPi), as a kind of DNA damage repair inhibitor, has been shown to be effective in various solid tumors and hematologic malignancies. Natural killer/T cell lymphoma (NKTCL) is a highly aggressive malignancy, the treatment of which has long been a major challenge in the c...
Autores principales: | Wu, Jiazhuo, Shi, Cunzhen, Li, Hongwen, Song, Wenting, Huang, Shuo, Zhang, Jianxiang, Li, Wencai, Li, Zhaoming, Zhang, Mingzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347840/ https://www.ncbi.nlm.nih.gov/pubmed/37442994 http://dx.doi.org/10.1186/s12916-023-02904-9 |
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