Pharmacovariome scanning using whole pharmacogene resequencing coupled with deep computational analysis and machine learning for clinical pharmacogenomics

BACKGROUND: This pilot study aims to identify and functionally assess pharmacovariants in whole exome sequencing data. While detection of known variants has benefited from pharmacogenomic-dedicated bioinformatics tools before, in this paper we have tested novel deep computational analysis in additio...

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Detalles Bibliográficos
Autores principales: Tafazoli, Alireza, Mikros, John, Khaghani, Faeze, Alimardani, Maliheh, Rafigh, Mahboobeh, Hemmati, Mahboobeh, Siamoglou, Stavroula, Golińska, Agnieszka Kitlas, Kamiński, Karol A., Niemira, Magdalena, Miltyk, Wojciech, Patrinos, George P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347842/
https://www.ncbi.nlm.nih.gov/pubmed/37452347
http://dx.doi.org/10.1186/s40246-023-00508-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10347842/
https://www.ncbi.nlm.nih.gov/pubmed/37452347
http://dx.doi.org/10.1186/s40246-023-00508-1

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