Transcriptomic analysis reveals the regulatory mechanism underlying the indirubin-mediated amelioration of dextran sulfate sodium-induced colitis in mice

CONTEXT: Aryl hydrocarbon receptor (AhR) agonists are potential therapeutic agents for ulcerative colitis (UC). Indirubin (IDR), which is a natural AhR ligand approved for leukemia treatment, ameliorates dextran sulfate sodium (DSS)-induced colitis in mice. However, the therapeutic mechanisms of IDR...

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Detalles Bibliográficos
Autores principales: Liu, Zhe, Zhang, Jin-ru, Huang, Yong-xiang, Li, Xue-ying, Zhu, Hai-peng, Yang, Rui-yi, Chen, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348027/
https://www.ncbi.nlm.nih.gov/pubmed/37439220
http://dx.doi.org/10.1080/13880209.2023.2233565

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