High-Dose Vitamin C Alleviates Pancreatic Necrosis by Inhibiting Platelet Activation Through the CXCL12/CXCR4 Pathway in Severe Acute Pancreatitis

BACKGROUND: Platelet activation in the early stage of pancreatitis is the key step developing into pancreatic necrosis. Studies suggested that vitamin C (Vit C) can inhibit platelet activity by targeting CXCL12/CXCR4 pathway. High-dose Vit C were showed to reduce pancreatic necrosis in severe acute...

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Detalles Bibliográficos
Autores principales: Gui, Menglu, Huang, Jun, Sheng, Huiqiu, Chen, Ying, Yang, Zhitao, Ma, Li, Wang, Daosheng, Xu, Lili, Sun, Wenwu, Liu, Junling, Xu, Yanyan, Chen, Erzhen, Zhao, Bing, Mao, Enqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10348372/
https://www.ncbi.nlm.nih.gov/pubmed/37456783
http://dx.doi.org/10.2147/JIR.S415974

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